Concepedia

Integrin-mediated Entry

Integrin-Mediated Entry is a viral entry mechanism in which pathogens exploit host cell integrins—transmembrane receptors involved in cell adhesion and signaling—as primary or co-receptors to facilitate internalization through ligand-receptor interactions and downstream cytoskeletal rearrangements.

203

Publications

21.5K

Citations

1K

Authors

359

Institutions

Publications per year

2017–2026

31

Parents

Publications

203

Integrins αvβ3 and αvβ5 promote adenovirus internalization but not virus attachment

Thomas J. Wickham, Patricia Mathias, David A. Cheresh et al. · Cell · 1993 · 2.2K citations

, , +16

Multiple β1 chain integrins are receptors for invasin, a protein that promotes bacterial penetration into mammalian cells

Ralph R. Isberg, John M. Leong · Cell · 1990 · 799 citations

, , +12

Adenovirus triggers macropinocytosis and endosomal leakage together with its clathrin-mediated uptake

Oliver Meier, Karin Boucke, Silvija Vig Hammer et al. · The Journal of Cell Biology · 2002 · 461 citations · Full text

, , +17

β <sub>3</sub> integrins mediate the cellular entry of hantaviruses that cause respiratory failure

Irina N. Gavrilovskaya, M P Shepley, Robert D. Shaw et al. · Proceedings of the National Academy of Sciences · 1998 · 410 citations · Full text

, , +17

Integrin α3β1 (CD 49c/29) Is a Cellular Receptor for Kaposi's Sarcoma-Associated Herpesvirus (KSHV/HHV-8) Entry into the Target Cells

Shaw M. Akula, Naranatt P. Pramod, Fu-Zhang Wang et al. · Cell · 2002 · 377 citations · Full text

, , +17

1–5 of 203

Authors

1K

  1. GR
    Glen R. Nemerow

    Scripps Research Institute, United States

    11 publications · 4.1K citations

    11

    h-index

  2. RR
    Ralph R. Isberg

    Tufts University, United States

    9 publications · 1.6K citations

    9

    h-index

  3. BC
    Bala Chandran

    Rosalind Franklin University of Medicine and Science, United States

    7 publications · 1.1K citations

    7

    h-index

  4. JM
    Jeffrey M. Bergelson

    Children's Hospital of Philadelphia, United States

    5 publications · 461 citations

    5

    h-index

  5. YT
    Yoshikazu Takada

    Scripps Research Institute, United States

    5 publications · 650 citations

    5

    h-index

1–5 of 1K

Institutions

359

  1. Scripps Research Institute

    San Diego, United States

    18 h-index

    50 publications

    18.3K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    11 h-index

    27 publications

    3.5K citations

  3. Tufts University

    Medford, United States

    9 h-index

    26 publications

    3.9K citations

  4. University of Wisconsin–Madison

    Madison, United States

    6 h-index

    17 publications

    2.6K citations

  5. The University of Melbourne

    Melbourne, Australia

    5 h-index

    19 publications

    2.1K citations

  6. University of Kansas Medical Center

    Kansas City, United States

    5 h-index

    20 publications

    3.6K citations

  7. University of Turku

    Turku, Finland

    5 h-index

    24 publications

    2.2K citations

  8. The Pirbright Institute

    Woking, United Kingdom

    4 h-index

    13 publications

    3.9K citations

1–8 of 359

Venues

  1. Journal of Virology

    JVI · 49 publications · 5.9K citations

    41

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 11 publications · 1.7K citations

    11

    h-index

  3. Virology

    11 publications · 741 citations

    11

    h-index

  4. Journal of Biological Chemistry

    JBC · 9 publications · 946 citations

    9

    h-index

  5. Cellular Microbiology

    8 publications · 489 citations

    8

    h-index

1–5