Concepedia

Insulator-mediated Looping

Insulator-Mediated Looping is a genomic regulatory mechanism in which insulator elements facilitate the formation of chromatin loops to modulate enhancer-promoter interactions by spatially segregating functional domains within the genome.

8

Publications

576

Citations

30

Authors

18

Institutions

Publications per year

2017–2026

2

Parents

Publications

8

CTCF-dependent enhancer-blocking by alternative chromatin loop formation

Chunhui Hou, Hui Zhao, Keiji Tanimoto et al. · Proceedings of the National Academy of Sciences · 2008 · 214 citations · Full text

, , +17

Epigenome editing strategies for the functional annotation of CTCF insulators

Daniel R. Tarjan, William Flavahan, B Bernstein · Nature Communications · 2019 · 94 citations · Full text

, , +17

Study of the Functional Interaction between Mcp Insulators from the <i>Drosophila bithorax</i> Complex: Effects of Insulator Pairing on Enhancer-Promoter Communication

Olga Kyrchanova, Stepan V. Toshchakov, Alexander Parshikov et al. · Molecular and Cellular Biology · 2007 · 69 citations · Full text

, , +17

DeepMILO: a deep learning approach to predict the impact of non-coding sequence variants on 3D chromatin structure

Tuan Trieu, Alexander Martinez‐Fundichely, Ekta Khurana · Genome biology · 2020 · 65 citations · Full text

, , +17

Mechanism of Chromosomal Boundary Action: Roadblock, Sink, or Loop?

Daryl M. Gohl, Tsutomu Aoki, Jason Blanton et al. · Genetics · 2011 · 60 citations · Full text

, , +12

1–5 of 8

Authors

30

  1. PG
    Pavel Georgiev

    Institute of Gene Biology, Russia

    2 publications · 110 citations

    2

    h-index

  2. DJ
    David J. Samuelson

    University of Wisconsin–Madison, United States

    1 publications · 22 citations

    1

    h-index

  3. GS
    Greg Shanower

    Princeton University, United States

    1 publications · 60 citations

    1

    h-index

  4. MT
    Ming Tang

    The University of Texas MD Anderson Cancer Center, United States

    1 publications · 11 citations

    1

    h-index

  5. DR
    Daniel R. Tarjan

    Harvard University, United States

    1 publications · 94 citations

    1

    h-index

1–5 of 30

Institutions

18

  1. Institute of Gene Biology

    Moscow, Russia

    2 h-index

    6 publications

    358 citations

  2. Cornell University

    Ithaca, United States

    1 h-index

    3 publications

    195 citations

  3. Princeton University

    Princeton, United States

    1 h-index

    6 publications

    360 citations

  4. Harvard University

    Cambridge, United States

    1 h-index

    3 publications

    282 citations

  5. Florida College

    Temple Terrace, United States

    1 h-index

    2 publications

    22 citations

  6. Geisinger Commonwealth School of Medicine

    Scranton, United States

    1 h-index

    1 publications

    60 citations

  7. University of Tsukuba

    Tsukuba, Japan

    1 h-index

    1 publications

    214 citations

  8. New York Hospital Queens

    New York, United States

    1 h-index

    1 publications

    65 citations

1–8 of 18

Venues

  1. Molecular and Cellular Biology

    MCB · 2 publications · 110 citations

    2

    h-index

  2. Genome biology

    1 publications · 65 citations

    1

    h-index

  3. Nature Communications

    1 publications · 94 citations

    1

    h-index

  4. Genetics

    1 publications · 60 citations

    1

    h-index

  5. Nucleic Acids Research

    1 publications · 22 citations

    1

    h-index

1–5