Concepedia

Insertion Site Effects

Insertion Site Effects is a phenomenon in transgenic organism development wherein the functional expression and stability of an inserted transgene are influenced by the genomic context and regulatory elements at the site of integration, thereby distinguishing it from predictable, position-independent transgene expression.

272

Publications

17.8K

Citations

1.3K

Authors

464

Institutions

Publications per year

2017–2026

30

Variants

Position Effects

Parents

Publications

272

The Berkeley Drosophila Genome Project Gene Disruption Project: Single P-Element Insertions Mutating 25% of Vital Drosophila Genes

Allan C. Spradling, Dianne Stern, Amy Beaton et al. · Genetics · 1999 · 793 citations · Full text

, , +13

Intravascular Complications of Central Venous Catheterization by Insertion Site

Jean‐Jacques Parienti, Nicolas Mongardon, Bruno Mégarbane et al. · New England Journal of Medicine · 2015 · 776 citations · Full text

, , +13

Epstein-Barr virus latent membrane protein 1 is essential for B-lymphocyte growth transformation.

Kenneth M. Kaye, Kenneth M. Izumi, Elliott Kieff · Proceedings of the National Academy of Sciences · 1993 · 773 citations · Full text

, , +13

DNA position-specific repression of transcription by a Drosophila zinc finger protein.

Pamela Geyer, Victor G. Corces · Genes & Development · 1992 · 426 citations · Full text

, , +17

Differential impact of allelic ratio and insertion site in FLT3-ITD–positive AML with respect to allogeneic transplantation

Richard F. Schlenk, Sabine Käyser, Lars Bullinger et al. · Blood · 2014 · 400 citations · Full text

, , +3

1–5 of 272

Authors

1.3K

  1. NV
    Nina V. Fedoroff

    Pennsylvania State University, United States

    3 publications · 302 citations

    3

    h-index

  2. AP
    Alain Pélisson

    Centre National de la Recherche Scientifique, France

    3 publications · 113 citations

    3

    h-index

  3. JB
    James B. Kaper

    University of Maryland, Baltimore, United States

    3 publications · 290 citations

    3

    h-index

  4. LC
    L. Curtis Hannah

    University of Florida, United States

    2 publications · 308 citations

    2

    h-index

  5. SS
    S. S. Pappu

    University of Georgia, United States

    2 publications · 31 citations

    2

    h-index

1–5 of 1.3K

Institutions

464

  1. Centre National de la Recherche Scientifique

    Paris, France

    11 h-index

    53 publications

    1.9K citations

  2. Inserm

    Paris, France

    7 h-index

    28 publications

    2.7K citations

  3. Yale University

    New Haven, United States

    6 h-index

    23 publications

    2.3K citations

  4. Harvard University

    Cambridge, United States

    6 h-index

    23 publications

    4.3K citations

  5. Stanford University

    Stanford, United States

    6 h-index

    17 publications

    2.6K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    5 h-index

    17 publications

    6.8K citations

  7. Department of Embryology

    Baltimore, United States

    4 h-index

    8 publications

    2.9K citations

  8. University of Chicago

    Chicago, United States

    4 h-index

    11 publications

    1.3K citations

1–8 of 464

Venues

  1. Journal of Bacteriology

    JB · 19 publications · 1.1K citations

    18

    h-index

  2. Genetics

    14 publications · 1.6K citations

    14

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 12 publications · 2.3K citations

    12

    h-index

  4. Nucleic Acids Research

    10 publications · 522 citations

    10

    h-index

  5. Molecular and Cellular Biology

    MCB · 7 publications · 318 citations

    7

    h-index

1–5