Concepedia

Immediate-release Tacrolimus

Immediate-Release Tacrolimus is a pharmaceutical formulation of the calcineurin inhibitor tacrolimus designed for rapid dissolution and absorption following oral administration, distinguished from extended-release formulations by its pharmacokinetic profile that achieves peak blood concentrations within hours to support precise therapeutic drug monitoring and dosing flexibility in immunosuppressive regimens.

65

Publications

2.6K

Citations

594

Authors

268

Institutions

Publications per year

2017–2026

28

Variants

Ir-tacrolimus

Parents

Publications

65

Efficacy and safety of tacrolimus compared with ciclosporin microemulsion in renal transplantation: a randomised multicentre study

Raimund Margreiter · The Lancet · 2002 · 450 citations

, , +13

One-Year Results with Extended-Release Tacrolimus/MMF, Tacrolimus/MMF and Cyclosporine/MMF in De Novo Kidney Transplant Recipients

H lio Tedesco Silva, H C Yang, Marwan Abouljoud et al. · American Journal of Transplantation · 2007 · 177 citations

, , +16

A Steady-State Head-to-Head Pharmacokinetic Comparison of All FK-506 (Tacrolimus) Formulations (ASTCOFF): An Open-Label, Prospective, Randomized, Two-Arm, Three-Period Crossover Study

Simon Tremblay, V. Nigro, Joanne Weinberg et al. · American Journal of Transplantation · 2016 · 162 citations · Full text

, , +15

Conversion of Stable Kidney Transplant Recipients From a Twice Daily Prograf-Based Regimen to a Once Daily Modified Release Tacrolimus-Based Regimen

Rita R. Alloway, S. Steinberg, Khalid Khalil et al. · Transplantation Proceedings · 2005 · 161 citations

, , +16

Five-Year Results of a Randomized, Single-Center Study of Tacrolimus vs Microemulsion Cyclosporine in Heart Transplant Patients

Jon Kobashigawa, J. Patel, Hiroshi Furukawa et al. · The Journal of Heart and Lung Transplantation · 2006 · 103 citations

, , +17

1–5 of 65

Authors

594

  1. JS
    Jeffrey S. Zaltzman

    St. Michael's Hospital, Canada

    5 publications · 212 citations

    5

    h-index

  2. WE
    William E. Fitzsimmons

    Astellas Pharma (United States), United States

    5 publications · 512 citations

    5

    h-index

  3. MR
    M. Roy First

    University of Cincinnati, United States

    4 publications · 491 citations

    4

    h-index

  4. KW
    K. Wisemandle

    Astellas Pharma (United States), United States

    4 publications · 491 citations

    4

    h-index

  5. RR
    Rita R. Alloway

    University of Cincinnati, United States

    4 publications · 477 citations

    4

    h-index

1–5 of 594

Institutions

268

  1. Inserm

    Paris, France

    6 h-index

    22 publications

    357 citations

  2. Heidelberg University

    Heidelberg, Germany

    5 h-index

    23 publications

    830 citations

  3. University of Toronto

    Toronto, Canada

    5 h-index

    15 publications

    336 citations

  4. St. Michael's Hospital

    Toronto, Canada

    4 h-index

    15 publications

    315 citations

  5. KU Leuven

    Leuven, Belgium

    4 h-index

    4 publications

    101 citations

  6. Astellas Pharma (United States)

    Northbrook, United States

    4 h-index

    20 publications

    1.7K citations

  7. Assistance Publique – Hôpitaux de Paris

    Paris, France

    4 h-index

    26 publications

    358 citations

  8. Astellas Pharma (Japan)

    Tokyo, Japan

    3 h-index

    6 publications

    150 citations

1–8 of 268

Venues

  1. Transplantation Proceedings

    18 publications · 554 citations

    13

    h-index

  2. Transplant International

    6 publications · 92 citations

    6

    h-index

  3. Transplantation

    4 publications · 64 citations

    4

    h-index

  4. Clinical Transplantation

    3 publications · 93 citations

    3

    h-index

  5. American Journal of Transplantation

    3 publications · 399 citations

    3

    h-index

1–5