Concepedia

Hypothalamic Axis Aging

Hypothalamic Axis Aging is a theoretical construct within neuroendocrine aging that refers to the progressive dysregulation of hypothalamic-pituitary signaling pathways, distinguishing it from peripheral endocrine decline by emphasizing central nervous system-driven alterations in hormonal homeostasis.

70

Publications

2.8K

Citations

299

Authors

132

Institutions

Publications per year

2017–2026

4

Parents

Publications

70

Impaired leptin responsiveness in aged rats.

P. J. Scarpace, Michael E. Matheny, R L Moore et al. · Diabetes · 2000 · 155 citations · Full text

, , +14

Cortisol Secretion in Relation to Age in Major Depression1

Gregory M. Asnis, Edward J. Sachar, Uriel Halbreich et al. · Psychosomatic Medicine · 1981 · 139 citations

, , +17

Age-related insulin resistance in hypothalamus and peripheral tissues of orexin knockout mice

Hiroshi Tsuneki, Shin‐ichi Murata, Yuuki Anzawa et al. · Diabetologia · 2008 · 121 citations · Full text

, , +16

Increased Hypothalamic Protein Tyrosine Phosphatase 1B Contributes to Leptin Resistance with Age

Christopher D. Morrison, Christy L. White, Zhong Wang et al. · Endocrinology · 2006 · 104 citations · Full text

, , +17

Differential and Age‐Dependent Effects of Maternal Deprivation on the Hypothalamic‐Pituitary‐Adrenal Axis of Brown Norway Rats from Youth to Senescence

Judith O Workel, Melly S. Oitzl, Marc Fluttert et al. · Journal of Neuroendocrinology · 2001 · 102 citations

, , +17

1–5 of 70

Authors

299

  1. AC
    Andrea C. Gore

    The University of Texas at Austin, United States

    3 publications · 138 citations

    3

    h-index

  2. JF
    James F. Nelson

    The University of Texas at San Antonio Health Science Center, United States

    3 publications · 107 citations

    3

    h-index

  3. AA
    Antonio Andrés

    University of Castilla-La Mancha, Spain

    2 publications · 111 citations

    2

    h-index

  4. YT
    Yoshitaka Tamada

    Kyoto Prefectural University of Medicine, Japan

    2 publications · 23 citations

    2

    h-index

  5. HF
    Henryk F. Urbanski

    Oregon National Primate Research Center, United States

    2 publications · 95 citations

    2

    h-index

1–5 of 299

Institutions

132

  1. McGill University

    Montreal, Canada

    3 h-index

    9 publications

    285 citations

  2. Augusta University

    Augusta, United States

    2 h-index

    5 publications

    267 citations

  3. University of Chinese Academy of Sciences

    Beijing, China

    2 h-index

    5 publications

    74 citations

  4. The University of Texas at San Antonio Health Science Center

    San Antonio, United States

    2 h-index

    3 publications

    79 citations

  5. Universidad Rey Juan Carlos

    Madrid, Spain

    2 h-index

    6 publications

    333 citations

  6. Oregon Health & Science University

    Portland, United States

    2 h-index

    3 publications

    167 citations

  7. The University of Texas at Austin

    Austin, United States

    2 h-index

    8 publications

    276 citations

  8. Leiden University Medical Center

    Leiden, The Netherlands

    2 h-index

    10 publications

    940 citations

1–8 of 132

Venues

  1. Endocrinology

    12 publications · 660 citations

    12

    h-index

  2. Neurobiology of Aging

    6 publications · 232 citations

    6

    h-index

  3. Neuroendocrinology

    4 publications · 71 citations

    4

    h-index

  4. Experimental Gerontology

    3 publications · 114 citations

    3

    h-index

  5. The Journal of Clinical Endocrinology & Metabolism

    JCEM · 3 publications · 182 citations

    3

    h-index

1–5