Concepedia

Hyperprogressive Disease

Hyperprogressive Disease is a clinical phenomenon observed in oncology whereby, following initiation of checkpoint inhibitor therapy, a patient exhibits an abrupt and substantial acceleration in tumor growth rate that exceeds the expected progression seen in untreated disease.

76

Publications

7.6K

Citations

681

Authors

261

Institutions

Publications per year

2017–2026

73

Variants

HpdHyper-progressive Disease

Parents

Publications

76

Hyperprogressive Disease Is a New Pattern of Progression in Cancer Patients Treated by Anti-PD-1/PD-L1

Stéphane Champiat, Laurent Dercle, Samy Ammari et al. · Clinical Cancer Research · 2016 · 1.2K citations

, , +17

PD-1 <sup>+</sup> regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer

Takahiro Kamada, Yosuke Togashi, Christopher Tay et al. · Proceedings of the National Academy of Sciences · 2019 · 1K citations · Full text

, , +17

Hyperprogressors after Immunotherapy: Analysis of Genomic Alterations Associated with Accelerated Growth Rate

Shumei Kato, Aaron M. Goodman, Vighnesh Walavalkar et al. · Clinical Cancer Research · 2017 · 852 citations · Full text

, , +17

Hyperprogressive Disease in Patients With Advanced Non–Small Cell Lung Cancer Treated With PD-1/PD-L1 Inhibitors or With Single-Agent Chemotherapy

Roberto Ferrara, Laura Mezquita, Matthieu Texier et al. · JAMA Oncology · 2018 · 738 citations · Full text

, , +14

Antibody–Fc/FcR Interaction on Macrophages as a Mechanism for Hyperprogressive Disease in Non–small Cell Lung Cancer Subsequent to PD-1/PD-L1 Blockade

Giuseppe Lo Russo, Massimo Moro, Michele Sommariva et al. · Clinical Cancer Research · 2018 · 407 citations · Full text

, , +17

1–5 of 76

Authors

681

  1. RF
    Roberto Ferrara

    Fondazione IRCCS Istituto Nazionale dei Tumori, Italy

    6 publications · 987 citations

    6

    h-index

  2. JS
    Jong‐Mu Sun

    Samsung Medical Center, South Korea

    4 publications · 161 citations

    4

    h-index

  3. JS
    Jin Seok Ahn

    Samsung Medical Center, South Korea

    4 publications · 161 citations

    4

    h-index

  4. LM
    Laura Mezquita

    Institut Gustave Roussy, France

    4 publications · 897 citations

    4

    h-index

  5. SL
    Se‐Hoon Lee

    Samsung Medical Center, South Korea

    4 publications · 161 citations

    4

    h-index

1–5 of 681

Institutions

261

  1. Samsung Medical Center

    Seoul, South Korea

    6 h-index

    34 publications

    1.9K citations

  2. Yonsei University

    Seoul, South Korea

    6 h-index

    19 publications

    2.5K citations

  3. Sungkyunkwan University

    Seoul, South Korea

    6 h-index

    37 publications

    2.2K citations

  4. National Cancer Center Hospital East

    Kashiwa, Japan

    5 h-index

    40 publications

    8.9K citations

  5. Institut Gustave Roussy

    Villejuif, France

    5 h-index

    57 publications

    25.6K citations

  6. Ulsan College

    Ulsan, South Korea

    5 h-index

    9 publications

    259 citations

  7. University of Ulsan

    Ulsan, South Korea

    5 h-index

    9 publications

    259 citations

  8. Fondazione IRCCS Istituto Nazionale dei Tumori

    Milan, Italy

    5 h-index

    27 publications

    8.1K citations

1–8 of 261

Venues

  1. Clinical Cancer Research

    5 publications · 2.6K citations

    5

    h-index

  2. Journal for ImmunoTherapy of Cancer

    JITC · 5 publications · 384 citations

    5

    h-index

  3. Journal of Clinical Oncology

    4 publications · 100 citations

    4

    h-index

  4. Annals of Oncology

    3 publications · 359 citations

    3

    h-index

  5. Thoracic Cancer

    2 publications · 63 citations

    2

    h-index

1–5