Concepedia

Hypermutation Systems

Hypermutation Systems is a computational framework within diversity generation that enables targeted, high-frequency variation in specific components of a system to accelerate the exploration of novel solutions while maintaining overall structural integrity.

27

Publications

1.4K

Citations

173

Authors

94

Institutions

Publications per year

2017–2026

7

Parents

Publications

27

In vivo hypermutation and continuous evolution

Rosana S. Molina, Gordon Rix, Amanuella A. Mengiste et al. · Nature Reviews Methods Primers · 2022 · 141 citations · Full text

, , +10

Rabbit IgH sequences in appendix germinal centers: VH diversification by gene conversion-like and hypermutation mechanisms

P D Weinstein, Arthur O. Anderson, Rose G. Maget · Immunity · 1994 · 140 citations

, , +12

Frequent occurrence of B‐cell lymphomas in angioimmunoblastic T‐cell lymphoma and proliferation of Epstein–Barr virus‐infected cells in early cases

Klaus Willenbrock, Andreas Bräuninger, Martin‐Leo Hansmann · British Journal of Haematology · 2007 · 129 citations · Full text

, , +16

AID/APOBEC cytosine deaminase induces genome-wide kataegis

Artem G. Lada, Alok Dhar, Robert Boissy et al. · Biology Direct · 2012 · 105 citations · Full text

, , +12

Innate Immune Signaling Induces High Levels of TC-specific Deaminase Activity in Primary Monocyte-derived Cells through Expression of APOBEC3A Isoforms

Beth K Thielen, John McNevin, M. Juliana McElrath et al. · Journal of Biological Chemistry · 2010 · 104 citations · Full text

, , +16

1–5 of 27

Authors

173

  1. CC
    Chang C. Liu

    University of California, Irvine, United States

    3 publications · 237 citations

    3

    h-index

  2. SK
    Seokhee Kim

    Seoul National University, South Korea

    2 publications · 199 citations

    2

    h-index

  3. JE
    John E. Dueber

    University of California, Berkeley, United States

    2 publications · 199 citations

    2

    h-index

  4. ZH
    Zachary Heins

    The University of Texas MD Anderson Cancer Center, United States

    2 publications · 199 citations

    2

    h-index

  5. AS
    Ahmad S. Khalil

    Boston University, United States

    2 publications · 199 citations

    2

    h-index

1–5 of 173

Institutions

94

  1. University of California, Irvine

    Irvine, United States

    3 h-index

    8 publications

    673 citations

  2. Broad Institute

    Cambridge, United States

    2 h-index

    3 publications

    257 citations

  3. Boston University

    Boston, United States

    2 h-index

    4 publications

    398 citations

  4. California Institute of Technology

    Pasadena, United States

    2 h-index

    4 publications

    398 citations

  5. Tecnológico de Monterrey

    Monterrey, Mexico

    2 h-index

    2 publications

    199 citations

  6. Massachusetts Institute of Technology

    Cambridge, United States

    2 h-index

    4 publications

    398 citations

  7. Innovative Genomics Institute

    Berkeley, United States

    2 h-index

    3 publications

    257 citations

  8. Seoul National University

    Seoul, South Korea

    2 h-index

    4 publications

    398 citations

1–8 of 94

Venues

  1. Nature Reviews Methods Primers

    2 publications · 199 citations

    2

    h-index

  2. British Journal of Haematology

    BJH · 2 publications · 186 citations

    2

    h-index

  3. Journal of Viral Hepatitis

    2 publications · 49 citations

    2

    h-index

  4. Trends in Genetics

    TIG · 1 publications · 18 citations

    1

    h-index

  5. Retrovirology

    1 publications · 20 citations

    1

    h-index

1–5