Hydrotropic Solubilization

Hydrotropic Solubilization is a solubilization method in which the aqueous solubility of poorly soluble compounds is enhanced through the action of hydrotropic agents that aggregate above a critical concentration to form molecular assemblies capable of solubilizing hydrophobic solutes without forming true micelles characteristic of surfactants.

Publications

4.6K

Citations

282

Authors

Institutions

Publications per year

2017–2026

Parents

Solubility Enhancement

Publications

Hydrotropic solubilization of zinc acetates for sustainable aqueous battery electrolytes

Dejian Dong, Tairan Wang, Yue Sun et al. · Nature Sustainability · 2023 · 376 citations

Natural Sciences, Chemical Engineering, Materials Science +16

Hydrotropic Solubilization of Paclitaxel: Analysis of Chemical Structures for Hydrotropic Property

Jaehwi Lee, Sang Cheon Lee, Ghanashyam Acharya et al. · Pharmaceutical Research · 2003 · 188 citations

Pharmacy, Medicinal Chemistry, Pharmaceutics +13

Unified Concept of Solubilization in Water by Hydrotropes and Cosolvents

Pierre Bauduin, A. Renoncourt, Adrian H. Kopf et al. · Langmuir · 2005 · 159 citations

Natural Sciences, Chemical Engineering, Chemistry +17

Hydrotropic Solubilization of Poorly Water-Soluble Drugs

Ji Young Kim, Sungwon Kim, M. Papp et al. · Journal of Pharmaceutical Sciences · 2010 · 143 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +14

Hydrotropic Dendrimers of Generations 4 and 5: Synthesis, Characterization, and Hydrotropic Solubilization of Paclitaxel

Tooru Ooya, Jaehwi Lee, Kinam Park · Bioconjugate Chemistry · 2004 · 136 citations

Pharmacy, Pharmaceutics, Pharmacology +17

1–5 of 99

Authors

282

SS
Seishi Shimizu
University of York, United Kingdom
7 publications · 485 citations
7
h-index
JA
João A. P. Coutinho
University of Aveiro, Portugal
6 publications · 171 citations
6
h-index
DO
Dinis O. Abranches
University of Aveiro, Portugal
6 publications · 171 citations
6
h-index
RM
RK Maheshwari
Indian Institute of Technology Indore, India
5 publications · 160 citations
5
h-index
NJ
NK Jain
Dr. Hari Singh Gour University, India
4 publications · 137 citations
4
h-index

1–5 of 282

Institutions

1–8 of 92

Venues

Journal of Pharmaceutical Sciences
6 publications · 373 citations
6
h-index
The Journal of Physical Chemistry B
6 publications · 370 citations
6
h-index
Indian Journal of Pharmaceutical Sciences
6 publications · 175 citations
6
h-index
Asian Journal of Pharmaceutics
AJP · 5 publications · 85 citations
5
h-index
International Journal of Pharmaceutics
4 publications · 270 citations
4
h-index

1–5