Concepedia

Hydrophobic Insertion

Hydrophobic Insertion is a molecular interaction mechanism in which a protein domain or peptide segment penetrates into a lipid bilayer by partitioning nonpolar amino acid residues into the hydrophobic core of the membrane, driven by the exclusion of nonpolar surfaces from aqueous environments.

112

Publications

8.2K

Citations

483

Authors

206

Institutions

Publications per year

2017–2026

19

Parents

Publications

112

Molecular dynamics simulations suggest a mechanism for translocation of the HIV-1 TAT peptide across lipid membranes

Henry D. Herce, Angel E. Garcı́a · Proceedings of the National Academy of Sciences · 2007 · 465 citations · Full text

, , +17

The nature of the hydrophobic binding of small peptides at the bilayer interface: implications for the insertion of transbilayer helices

Russell E. Jacobs, Stephen H. White · Biochemistry · 1989 · 436 citations · Full text

, , +16

The Hydrophobic Insertion Mechanism of Membrane Curvature Generation by Proteins

Felix Campelo, Harvey T. McMahon, Michael M. Kozlov · Biophysical Journal · 2008 · 401 citations · Full text

, , +14

cDNA Sequence and mRNA Tissue Distribution of a Novel Human Matrix Metalloproteinase with a Potential Transmembrane Segment

Horst Will, Bernd Hinzmann · European Journal of Biochemistry · 1995 · 313 citations

, , +14

Three Arabidopsis Fatty Acyl-Coenzyme A Reductases, FAR1, FAR4, and FAR5, Generate Primary Fatty Alcohols Associated with Suberin Deposition   

Frédéric Domergue, Sollapura J. Vishwanath, Jérôme Joubès et al. · PLANT PHYSIOLOGY · 2010 · 300 citations · Full text

, , +13

1–5 of 112

Authors

483

  1. KT
    Kostas Tokatlidis

    University of Crete, Greece

    3 publications · 176 citations

    3

    h-index

  2. SH
    Stephen H. White

    University of California, Irvine, United States

    3 publications · 572 citations

    3

    h-index

  3. TG
    Tatiana G. Kutateladze

    University of Colorado Denver, United States

    3 publications · 165 citations

    3

    h-index

  4. MO
    Michael Overduin

    University of Birmingham, United Kingdom

    3 publications · 165 citations

    3

    h-index

  5. DJ
    David J. Thornton

    University of Manchester, United Kingdom

    2 publications · 166 citations

    2

    h-index

1–5 of 483

Institutions

206

  1. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    20 publications

    3.7K citations

  2. University of California San Diego

    San Diego, United States

    4 h-index

    16 publications

    1.3K citations

  3. University of Basel

    Basel, Switzerland

    3 h-index

    9 publications

    1.3K citations

  4. University of Colorado Health

    Aurora, United States

    3 h-index

    14 publications

    704 citations

  5. University of California, Irvine

    Irvine, United States

    3 h-index

    4 publications

    680 citations

  6. Columbia University

    New York, United States

    3 h-index

    12 publications

    1.7K citations

  7. University College London

    London, United Kingdom

    3 h-index

    8 publications

    544 citations

  8. Centre de Génétique Moléculaire

    Gif-sur-Yvette, France

    2 h-index

    3 publications

    142 citations

1–8 of 206

Venues

  1. Journal of Biological Chemistry

    JBC · 12 publications · 782 citations

    12

    h-index

  2. Biochemistry

    11 publications · 1.2K citations

    11

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 7 publications · 1.3K citations

    7

    h-index

  4. The Journal of Physical Chemistry B

    4 publications · 170 citations

    4

    h-index

  5. European Journal of Biochemistry

    EJB · 4 publications · 657 citations

    4

    h-index

1–5