Concepedia

Hydrolyzable Linkers

Hydrolyzable Linkers is a type of chemical linker designed to undergo cleavage through hydrolysis, distinguished by its susceptibility to degradation in aqueous environments, thereby enabling controlled release of conjugated molecules in applications such as drug delivery and bioconjugation.

44

Publications

3.7K

Citations

261

Authors

118

Institutions

Publications per year

2017–2026

14

Parents

Publications

44

Sacituzumab Govitecan in Metastatic Triple-Negative Breast Cancer

Aditya Bardia, Sara A. Hurvitz, Sara M. Tolaney et al. · New England Journal of Medicine · 2021 · 1.5K citations · Full text

, , +17

Synthesis and characterization of biodegradable polyurethane films based on HDI with hydrolyzable crosslinked bonds and a homogeneous structure for biomedical applications

Breno Rocha Barrioni, Sandhra M. Carvalho, Rodrigo Lambert Oréfice et al. · Materials Science and Engineering C · 2015 · 190 citations

, , +16

Degradable-Brushed pHEMA–pDMAEMA Synthesized via ATRP and Click Chemistry for Gene Delivery

Xulin Jiang, M.C. Lok, Wim E. Hennink · Bioconjugate Chemistry · 2007 · 189 citations

, , +17

Combinatorial Drug Conjugation Enables Nanoparticle Dual‐Drug Delivery

Santosh Aryal, Che‐Ming Jack Hu, Liangfang Zhang · Small · 2010 · 183 citations

, , +17

A new class of polymerizable dextrans with hydrolyzable groups: hydroxyethyl methacrylated dextran with and without oligolactate spacer

W.N.E. van Dijk-Wolthuls, Stellar K. Y. Tsang, J.J. Kettenes-van den BoschW.E. Hennink · Polymer · 1997 · 166 citations

, , +8

1–5 of 44

Authors

261

  1. CS
    Costas S. Patrickios

    University of Cyprus, Cyprus

    5 publications · 203 citations

    5

    h-index

  2. AB
    Aditya Bardia

    Massachusetts General Hospital, United States

    4 publications · 1.7K citations

    4

    h-index

  3. ET
    Efrosyni Themistou

    Queen's University Belfast, United Kingdom

    4 publications · 173 citations

    4

    h-index

  4. HS
    Hope S. Rugo

    University of California, San Francisco, United States

    4 publications · 1.7K citations

    4

    h-index

  5. JC
    Javier Cortés

    Vall d'Hebron Institute of Oncology, Spain

    3 publications · 1.7K citations

    3

    h-index

1–5 of 261

Institutions

118

  1. University of Cyprus

    Nicosia, Cyprus

    5 h-index

    11 publications

    452 citations

  2. UCSF Helen Diller Family Comprehensive Cancer Center

    San Francisco, United States

    4 h-index

    4 publications

    1.7K citations

  3. University of California, San Francisco

    San Francisco, United States

    4 h-index

    4 publications

    1.7K citations

  4. Vall d'Hebron Institute of Oncology

    Barcelona, Spain

    4 h-index

    4 publications

    1.7K citations

  5. Massachusetts General Hospital

    Boston, United States

    4 h-index

    4 publications

    1.7K citations

  6. Centre Eugène Marquis

    Rennes, France

    3 h-index

    3 publications

    1.6K citations

  7. UCLA Jonsson Comprehensive Cancer Center

    Los Angeles, United States

    3 h-index

    3 publications

    1.6K citations

  8. KU Leuven

    Leuven, Belgium

    3 h-index

    3 publications

    1.6K citations

1–8 of 118

Venues

  1. Macromolecules

    9 publications · 391 citations

    9

    h-index

  2. Polymer

    2 publications · 192 citations

    2

    h-index

  3. Journal of Clinical Oncology

    2 publications · 53 citations

    2

    h-index

  4. Biomacromolecules

    2 publications · 63 citations

    2

    h-index

  5. Chemistry of Materials

    2 publications · 75 citations

    2

    h-index

1–5