Concepedia

Hybridoma Engineering

Hybridoma Engineering is a methodological framework within biotechnological research that integrates somatic cell fusion techniques with selective culturing strategies to generate stable hybrid cell lines capable of producing monoclonal antibodies with predefined antigen specificity.

201

Publications

7.8K

Citations

704

Authors

240

Institutions

Publications per year

2017–2026

9

Parents

Publications

201

Reshaping Human Antibodies: Grafting an Antilysozyme Activity

Martine Verhoeyen, César Milstein, Greg Winter · Science · 1988 · 346 citations

, , +17

Rabbit monoclonal antibodies: generating a fusion partner to produce rabbit-rabbit hybridomas.

H Spieker-Polet, P. Sethupathi, Pi-Chen Yam et al. · Proceedings of the National Academy of Sciences · 1995 · 209 citations

, , +16

A Novel Method of Preparing Rat-Monoclonal Antibody-Producing Hybridomas by Using Rat Medial Iliac Lymph Node Cells.

Yumiko Kishiro, Megumi Kagawa, Ichiro Naito et al. · Cell Structure and Function · 1995 · 191 citations · Full text

, , +16

Production of Monoclonal Antibodies

Wayne M. Yokoyama · Current Protocols in Cell Biology · 1999 · 169 citations

, , +17

Human hybridomas constructed with antigen-specific Epstein-Barr virus-transformed cell lines.

Danuta Kozbor, A. Lagarde, John Roder · Proceedings of the National Academy of Sciences · 1982 · 161 citations · Full text

, , +13

1–5 of 201

Authors

704

  1. MA
    Mohamed Al‐Rubeai

    University of Birmingham, United Kingdom

    6 publications · 371 citations

    6

    h-index

  2. WM
    Wayne M. Yokoyama

    Howard Hughes Medical Institute, United States

    5 publications · 358 citations

    5

    h-index

  3. MT
    Michiyuki Tokashiki

    Teijin (Japan), Japan

    3 publications · 178 citations

    3

    h-index

  4. RM
    R. Mutharasan

    Drexel University, United States

    3 publications · 125 citations

    3

    h-index

  5. SO
    Steve Oh

    Bioprocessing Technology Institute, Singapore

    3 publications · 286 citations

    3

    h-index

1–5 of 704

Institutions

240

  1. University of Birmingham

    Birmingham, United Kingdom

    6 h-index

    22 publications

    1.4K citations

  2. Washington University in St. Louis

    St Louis, United States

    5 h-index

    5 publications

    359 citations

  3. Drexel University

    Philadelphia, United States

    4 h-index

    12 publications

    457 citations

  4. National Institutes of Health

    Bethesda, United States

    4 h-index

    9 publications

    399 citations

  5. University of Surrey

    Guildford, United Kingdom

    3 h-index

    10 publications

    269 citations

  6. University of Tsukuba

    Tsukuba, Japan

    3 h-index

    5 publications

    91 citations

  7. The University of Queensland

    Brisbane, Australia

    3 h-index

    7 publications

    88 citations

  8. Dutch Blood Transfusion Society

    Amsterdam, Netherlands

    3 h-index

    6 publications

    76 citations

1–8 of 240

Venues

  1. Journal of Immunological Methods

    24 publications · 1.2K citations

    20

    h-index

  2. Cytotechnology

    21 publications · 543 citations

    14

    h-index

  3. Journal of Biotechnology

    12 publications · 640 citations

    12

    h-index

  4. Methods in enzymology on CD-ROM/Methods in enzymology

    Book series · 8 publications · 188 citations

    8

    h-index

  5. Biotechnology Letters

    7 publications · 254 citations

    7

    h-index

1–5