Human systems integration is an interdisciplinary field and methodological approach focused on the systematic consideration of human capabilities, limitations, and needs throughout the entire system lifecycle, from conception through disposal. It investigates the complex interactions between humans and system components across various domains, such as human factors engineering, manpower, personnel, training, safety, and habitability. Characterized by its holistic and integrative perspective, its significance lies in optimizing overall system performance, enhancing human effectiveness, mitigating risks, and ensuring the development of safe, efficient, and sustainable systems.