Concepedia

Host-directed Drug Repurposing

Host-Directed Drug Repurposing is a drug repurposing strategy that targets host cellular factors and pathways to modulate infectious disease outcomes, distinguishing itself from pathogen-directed approaches by focusing on the host's biological mechanisms rather than microbial components.

14

Publications

597

Citations

117

Authors

48

Institutions

Publications per year

2017–2026

13

Parents

Publications

14

Drug synergy of combinatory treatment with remdesivir and the repurposed drugs fluoxetine and itraconazole effectively impairs SARS‐CoV‐2 infection in vitro

Sebastian Schloer, Linda Brunotte, Angeles Mecate‐Zambrano et al. · British Journal of Pharmacology · 2021 · 110 citations · Full text

, , +16

Old Weapon for New Enemy: Drug Repurposing for Treatment of Newly Emerging Viral Diseases

Deyin Guo · Virologica Sinica · 2020 · 87 citations · Full text

, , +16

Paracetamol-Induced Glutathione Consumption: Is There a Link With Severe COVID-19 Illness?

Piero Sestili, Carmela Fimognari · Frontiers in Pharmacology · 2020 · 55 citations · Full text

, , +16

Host transcriptome-guided drug repurposing for COVID-19 treatment: a meta-analysis based approach

Tamizhini Loganathan, Srimathy Ramachandran, Prakash Shankaran et al. · PeerJ · 2020 · 53 citations · Full text

, , +17

Host-directed drug therapy for tuberculosis

Reto Guler, Frank Brombacher · Nature Chemical Biology · 2015 · 48 citations

, , +10

1–5 of 14

Authors

117

  1. ML
    Michal Letek

    Universidad de León, Spain

    2 publications · 58 citations

    2

    h-index

  2. NB
    Natalia Bravo-Santano

    University of Roehampton, United Kingdom

    2 publications · 58 citations

    2

    h-index

  3. YC
    Yolanda Calle

    King's College London, United Kingdom

    2 publications · 58 citations

    2

    h-index

  4. LM
    Luís M. Mateos

    Universidad de León, Spain

    2 publications · 58 citations

    2

    h-index

  5. VB
    Volker Behrends

    Imperial College London, United Kingdom

    2 publications · 58 citations

    2

    h-index

1–5 of 117

Institutions

48

  1. University of Roehampton

    London, United Kingdom

    2 h-index

    13 publications

    442 citations

  2. Universidad de León

    León, Spain

    2 h-index

    2 publications

    58 citations

  3. Maison des Sciences sociales et des Humanités de Dijon

    Dijon, France

    1 h-index

    2 publications

    72 citations

  4. Children's National

    Washington, United States

    1 h-index

    3 publications

    66 citations

  5. Inserm

    Paris, France

    1 h-index

    3 publications

    108 citations

  6. Ankara Yıldırım Beyazıt University

    Ankara, Türkiye

    1 h-index

    1 publications

    36 citations

  7. Sun Yat-sen University

    Guangzhou, China

    1 h-index

    1 publications

    87 citations

  8. Chinese Academy of Sciences

    Beijing, China

    1 h-index

    1 publications

    36 citations

1–8 of 48

Venues

  1. mBio

    3 publications · 90 citations

    3

    h-index

  2. Scientific Reports

    2 publications · 58 citations

    2

    h-index

  3. Nature Chemical Biology

    1 publications · 48 citations

    1

    h-index

  4. Frontiers in Pharmacology

    1 publications · 55 citations

    1

    h-index

  5. British Journal of Pharmacology

    BJP · 1 publications · 110 citations

    1

    h-index

1–5