Concepedia

Hormone Deiodination

Hormone Deiodination is a biochemical process belonging to the class of hormone inactivation mechanisms, specifically characterized by the enzymatic removal of iodine atoms from iodothyronines to regulate thyroid hormone activity.

440

Publications

21.2K

Citations

1.1K

Authors

352

Institutions

Publications per year

2017–2026

15

Parents

Publications

440

Biochemistry, Cellular and Molecular Biology, and Physiological Roles of the Iodothyronine Selenodeiodinases

Antônio C. Bianco · Endocrine Reviews · 2002 · 424 citations · Full text

, , +15

Cloning of the mammalian type II iodothyronine deiodinase. A selenoprotein differentially expressed and regulated in human and rat brain and other tissues.

Walburga Croteau, Jennifer C. Davey, Valerie Anne Galton et al. · Journal of Clinical Investigation · 1996 · 387 citations · Full text

, , +11

The type 2 iodothyronine deiodinase is expressed primarily in glial cells in the neonatal rat brain

Ana Guadaño‐Ferraz, Marı́a Jesús Obregón, Donald L. St. Germain et al. · Proceedings of the National Academy of Sciences · 1997 · 368 citations

, , +16

Targeted Disruption of the Type 2 Selenodeiodinase Gene (<i>DIO</i>2) Results in a Phenotype of Pituitary Resistance to T<sub>4</sub>

Mark J. Schneider, Steven Fiering, Sophie Pallud et al. · Molecular Endocrinology · 2001 · 362 citations · Full text

, , +13

Type 3 deiodinase is critical for the maturation and function of the thyroid axis

Arturo Hernández · Journal of Clinical Investigation · 2006 · 342 citations · Full text

, , +17

1–5 of 440

Authors

1.1K

  1. TJ
    Theo J. Visser

    Erasmus MC, Netherlands

    40 publications · 2.2K citations

    28

    h-index

  2. JL
    Jack L. Leonard

    University of Massachusetts Chan Medical School, United States

    23 publications · 1.9K citations

    21

    h-index

  3. VD
    Veerle Darras

    KU Leuven, Belgium

    20 publications · 1K citations

    18

    h-index

  4. JK
    Josef Köhrle

    Charité - Universitätsmedizin Berlin, Germany

    19 publications · 845 citations

    17

    h-index

  5. DL
    Donald L. St. Germain

    Dartmouth College, United States

    18 publications · 2.3K citations

    16

    h-index

1–5 of 1.1K

Institutions

352

  1. Brigham and Women's Hospital

    Boston, United States

    29 h-index

    103 publications

    9K citations

  2. Harvard University

    Cambridge, United States

    28 h-index

    113 publications

    7.8K citations

  3. Erasmus MC

    Rotterdam, The Netherlands

    26 h-index

    92 publications

    3.4K citations

  4. KU Leuven

    Leuven, Belgium

    22 h-index

    95 publications

    5.6K citations

  5. Erasmus University Rotterdam

    Rotterdam, The Netherlands

    21 h-index

    76 publications

    4.4K citations

  6. University of Manitoba

    Winnipeg, Canada

    15 h-index

    38 publications

    1.3K citations

  7. Dartmouth College

    Hanover, United States

    15 h-index

    42 publications

    4.2K citations

  8. University of Massachusetts Chan Medical School

    Worcester, United States

    14 h-index

    39 publications

    1.7K citations

1–8 of 352

Venues

  1. Endocrinology

    121 publications · 5.4K citations

    42

    h-index

  2. The Journal of Clinical Endocrinology & Metabolism

    JCEM · 26 publications · 1.8K citations

    21

    h-index

  3. Journal of Clinical Investigation

    JCI · 22 publications · 2.2K citations

    20

    h-index

  4. General and Comparative Endocrinology

    26 publications · 1.1K citations

    20

    h-index

  5. Journal of Biological Chemistry

    JBC · 15 publications · 874 citations

    14

    h-index

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