Concepedia

Holliday Junction Resolution

Holliday Junction Resolution is a site-specific recombination process in which a specialized endonuclease catalyzes the cleavage and ligation of intertwined DNA strands at a Holliday junction, thereby resolving the four-way DNA intermediate into two separate duplex molecules with recombinant or restored genomic configurations.

275

Publications

18.2K

Citations

787

Authors

265

Institutions

Publications per year

2017–2026

22

Parents

Publications

275

Mus81-Eme1 Are Essential Components of a Holliday Junction Resolvase

Michael N. Boddy, Pierre-Henri L. Gaillard, W. Hayes McDonald et al. · Cell · 2001 · 526 citations · Full text

, , +8

The structure of the holliday junction, and its resolution

Derek R. Duckett, Alastair I.H. Murchie, Stephen Diekmann et al. · Cell · 1988 · 486 citations

, , +6

Mammalian BTBD12/SLX4 Assembles A Holliday Junction Resolvase and Is Required for DNA Repair

Jennifer M. Svendsen, Agata Smogorzewska, Mathew E. Sowa et al. · Cell · 2009 · 451 citations · Full text

, , +10

Human SLX4 Is a Holliday Junction Resolvase Subunit that Binds Multiple DNA Repair/Recombination Endonucleases

Samira Fekairi, Sarah Scaglione, Charly Chahwan et al. · Cell · 2009 · 416 citations · Full text

, , +12

Identification of Holliday junction resolvases from humans and yeast

Stephen C.Y. Ip, Ulrich Rass, Miguel G. Blanco et al. · Nature · 2008 · 415 citations · Full text

, , +9

1–5 of 275

Authors

787

  1. SC
    Stephen C. West

    Cancer Research UK, United Kingdom

    39 publications · 4.1K citations

    32

    h-index

  2. RG
    Robert G. Lloyd

    University of Nottingham, United Kingdom

    18 publications · 1.7K citations

    15

    h-index

  3. MC
    Matthew C. Whitby

    University of Oxford, United Kingdom

    14 publications · 1.2K citations

    14

    h-index

  4. GJ
    Gary J. Sharples

    Durham University, United Kingdom

    16 publications · 1.1K citations

    13

    h-index

  5. HI
    Hiroshi Iwasaki

    Fukuoka University, Japan

    13 publications · 1K citations

    13

    h-index

1–5 of 787

Institutions

265

  1. University of Oxford

    Oxford, United Kingdom

    20 h-index

    87 publications

    6.2K citations

  2. University of Dundee

    Dundee, United Kingdom

    17 h-index

    58 publications

    5.7K citations

  3. University of Nottingham

    Nottingham, United Kingdom

    15 h-index

    54 publications

    4.5K citations

  4. The Honourable Society of Lincoln's Inn

    London, United Kingdom

    15 h-index

    39 publications

    3.9K citations

  5. Queen's Medical Centre

    Nottingham, United Kingdom

    15 h-index

    60 publications

    5.4K citations

  6. Cancer Research UK

    London, United Kingdom

    14 h-index

    46 publications

    7.5K citations

  7. The University of Osaka

    Osaka, Japan

    12 h-index

    32 publications

    1.8K citations

  8. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    9 h-index

    23 publications

    1.5K citations

1–8 of 265

Venues

  1. Journal of Biological Chemistry

    JBC · 40 publications · 1.9K citations

    27

    h-index

  2. Nucleic Acids Research

    32 publications · 1.2K citations

    25

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 22 publications · 1.6K citations

    20

    h-index

  4. Journal of Molecular Biology

    JMB · 27 publications · 921 citations

    17

    h-index

  5. The EMBO Journal

    15 publications · 1.4K citations

    14

    h-index

1–5