Concepedia

Highly Variable Drug Comparison

Highly Variable Drug Comparison is a reference product comparison method that specifically addresses the bioequivalence assessment of highly variable drugs by employing scaled average bioequivalence or adaptive statistical approaches to account for intra-subject variability exceeding conventional thresholds.

11

Publications

384

Citations

33

Authors

18

Institutions

Publications per year

2017–2026

2

Parents

Publications

11

Drug Facts and Comparisons.

Annals of Internal Medicine · 1988 · 208 citations

, , +10

Non-traditional study designs to demonstrate average bioequivalence for highly variable drug products

Scott D. Patterson, Névine Zariffa, Timothy H. Montague et al. · European Journal of Clinical Pharmacology · 2001 · 39 citations

, , +16

On the leveling-off properties of the new bioequivalence limits for highly variable drugs of the EMA guideline

Vangelis Karalis, Mira Symillides, Panos Macheras · European Journal of Pharmaceutical Sciences · 2011 · 24 citations

, , +17

Meta-analysis of grip strength: most common, but superfluous variable in comparative NSAID trials.

Gøtzsche Pc · PubMed · 1989 · 21 citations

, , +15

Same drugs, valued differently? Comparing comparators and methods used in reimbursement recommendations in Australia, Canada, and Korea

Green Bae, Eun Young Bae, SeungJin Bae · Health Policy · 2015 · 19 citations

, , +9

1–5 of 11

Authors

33

  1. KH
    Kate Howland

    New Frontier, United States

    1 publications · 39 citations

    1

    h-index

  2. EY
    Eun Young Bae

    Korea Research Institute of Bioscience and Biotechnology, South Korea

    1 publications · 19 citations

    1

    h-index

  3. TH
    Timothy H. Montague

    GlaxoSmithKline (United States), United States

    1 publications · 39 citations

    1

    h-index

  4. MK
    Meinhard Kieser

    Heidelberg University, Germany

    1 publications · 10 citations

    1

    h-index

  5. KD
    Karlheinz Doser

    Hella (Germany), Germany

    1 publications · 10 citations

    1

    h-index

1–5 of 33

Institutions

18

  1. Daegu Catholic University

    Gyeongsan-si, South Korea

    1 h-index

    1 publications

    15 citations

  2. Amgen (United States)

    Thousand Oaks, United States

    1 h-index

    3 publications

    36 citations

  3. Peking University

    Beijing, China

    1 h-index

    2 publications

    20 citations

  4. Chungnam National University

    Daejeon, South Korea

    1 h-index

    3 publications

    45 citations

  5. GlaxoSmithKline (United States)

    Philadelphia, United States

    1 h-index

    4 publications

    156 citations

  6. Ewha Womans University

    Seoul, South Korea

    1 h-index

    2 publications

    38 citations

  7. University of Toronto

    Toronto, Canada

    1 h-index

    1 publications

    12 citations

  8. Gyeongju University

    Gyeongju, South Korea

    1 h-index

    1 publications

    19 citations

1–8 of 18

Venues

  1. European Journal of Clinical Pharmacology

    2 publications · 49 citations

    2

    h-index

  2. PubMed

    Repository · 2 publications · 31 citations

    2

    h-index

  3. European Journal of Pharmaceutical Sciences

    2 publications · 39 citations

    2

    h-index

  4. Statistics in Medicine

    1 publications · 12 citations

    1

    h-index

  5. Health Policy

    1 publications · 19 citations

    1

    h-index

1–5