Concepedia

High-level Transgene Expression

High-Level Transgene Expression is a molecular biology technique in chloroplast transformation that enables exceptionally elevated production of recombinant proteins by leveraging the high copy number of chloroplast genomes and strong regulatory elements to drive transgene transcription and translation.

250

Publications

22.3K

Citations

1.4K

Authors

446

Institutions

Publications per year

2017–2026

39

Parents

Publications

250

Efficient selection for high-expression transfectants with a novel eukaryotic vector

Hitoshi Niwa, Ken‐ichi Yamamura, Jun‐ichi Miyazaki · Gene · 1991 · 5.2K citations

, , +15

I-SceI meganuclease mediates highly efficient transgenesis in fish

Violette Thermes, Clemens Grabher, Filomena Ristoratore et al. · Mechanisms of Development · 2002 · 534 citations

, , +14

Efficient gene transfer into human hepatocytes by baculovirus vectors.

Christian Hofmann, Volker Sandig, Gary Jennings et al. · Proceedings of the National Academy of Sciences · 1995 · 496 citations

, , +15

Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo

Zhiying Chen, Cheng-Yi He, Anja Ehrhardt et al. · Molecular Therapy · 2003 · 464 citations

, , +17

‘ATG vectors’ for regulated high-level expression of cloned genes in Escherichia coli

Egon Amann, Jürgen Brosius · Gene · 1985 · 392 citations

, , +16

1–5 of 250

Authors

1.4K

  1. HD
    Henry Daniell

    University of Central Florida, United States

    10 publications · 919 citations

    10

    h-index

  2. PN
    Philip Ng

    Baylor College of Medicine, United States

    5 publications · 556 citations

    5

    h-index

  3. SP
    Saul Purton

    University College London, United Kingdom

    5 publications · 627 citations

    5

    h-index

  4. RB
    Ralph Bock

    Max Planck Institute of Molecular Plant Physiology, Germany

    5 publications · 632 citations

    5

    h-index

  5. TW
    Tianyun Wang

    Henan Medical University, China

    4 publications · 227 citations

    4

    h-index

1–5 of 1.4K

Institutions

446

  1. University College London

    London, United Kingdom

    9 h-index

    24 publications

    2.4K citations

  2. University of Central Florida

    Orlando, United States

    7 h-index

    18 publications

    2.1K citations

  3. Baylor College of Medicine

    Houston, United States

    7 h-index

    26 publications

    2.2K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    7 h-index

    31 publications

    4.5K citations

  5. Max Planck Institute of Molecular Plant Physiology

    Potsdam, Germany

    7 h-index

    24 publications

    2.4K citations

  6. Max Planck Society

    Munich, Germany

    6 h-index

    12 publications

    1.7K citations

  7. University of Pennsylvania

    Philadelphia, United States

    6 h-index

    32 publications

    1.8K citations

  8. University of Washington

    Seattle, United States

    6 h-index

    20 publications

    1.2K citations

1–8 of 446

Venues

  1. Molecular Therapy

    13 publications · 1.3K citations

    13

    h-index

  2. Human Gene Therapy

    10 publications · 705 citations

    10

    h-index

  3. The Plant Journal

    9 publications · 1.6K citations

    9

    h-index

  4. Plant Biotechnology Journal

    8 publications · 678 citations

    8

    h-index

  5. Applied Microbiology and Biotechnology

    7 publications · 457 citations

    7

    h-index

1–5