Concepedia

High-dose Tolerance

High-Dose Tolerance is a physiological mechanism of oral tolerance characterized by systemic immune unresponsiveness to dietary antigens achieved through the administration of high doses of antigen, leading to the induction of peripheral T-cell deletion or anergy.

187

Publications

9.7K

Citations

1.1K

Authors

325

Institutions

Publications per year

2017–2026

17

Parents

Publications

187

Induction of anergy or active suppression following oral tolerance is determined by antigen dosage.

Aharon Friedman, Howard L. Weiner · Proceedings of the National Academy of Sciences · 1994 · 635 citations

, , +16

High dose cytosine arabinoside (HDARAC) in refractory acute leukemia

Seth A. Rudnick, E Cadman, Robert L. Capizzi et al. · Cancer · 1979 · 287 citations · Full text

, , +17

Tolerance of Perovskite Solar Cell to High-Energy Particle Irradiations in Space Environment

Yu Miyazawa, M. Ikegami, Hsin–Wei Chen et al. · iScience · 2018 · 250 citations · Full text

, , +17

Identification of Rice Varieties with High Tolerance or Sensitivity to Lead and Characterization of the Mechanism of Tolerance

Young‐Yell Yang, Ji-Young Jung, Won‐Yong Song et al. · PLANT PHYSIOLOGY · 2000 · 245 citations · Full text

, , +17

High dose oral tolerance in ovalbumin TCR-transgenic mice: systemic neutralization of IL-12 augments TGF-beta secretion and T cell apoptosis

Thomas Marth, Warren Strober, Brian L. Kelsall · The Journal of Immunology · 1996 · 221 citations · Full text

, , +16

1–5 of 187

Authors

1.1K

  1. HL
    Howard L. Weiner

    Brigham and Women's Hospital, United States

    6 publications · 1.1K citations

    6

    h-index

  2. CK
    Chang‐Yuil Kang

    Seoul National University, South Korea

    3 publications · 90 citations

    3

    h-index

  3. KJ
    Kjell Jonsson

    Lund University, Sweden

    3 publications · 135 citations

    3

    h-index

  4. KR
    Kennedy R. Lees

    University of Glasgow, United Kingdom

    2 publications · 96 citations

    2

    h-index

  5. NL
    Norbert Lügering

    University of Münster, Germany

    2 publications · 198 citations

    2

    h-index

1–5 of 1.1K

Institutions

325

  1. Harvard University

    Cambridge, United States

    5 h-index

    11 publications

    2.2K citations

  2. Yale University

    New Haven, United States

    5 h-index

    30 publications

    3.1K citations

  3. Brigham and Women's Hospital

    Boston, United States

    5 h-index

    17 publications

    2.6K citations

  4. University of California, San Francisco

    San Francisco, United States

    5 h-index

    28 publications

    2.5K citations

  5. Western Infirmary

    Glasgow, United Kingdom

    4 h-index

    18 publications

    1.9K citations

  6. Seoul National University

    Seoul, South Korea

    4 h-index

    13 publications

    469 citations

  7. Johns Hopkins University

    Baltimore, United States

    4 h-index

    13 publications

    588 citations

  8. Stanford University

    Stanford, United States

    3 h-index

    11 publications

    1.6K citations

1–8 of 325

Venues

  1. The Journal of Immunology

    JI · 17 publications · 1.3K citations

    16

    h-index

  2. PubMed

    Repository · 19 publications · 678 citations

    14

    h-index

  3. IEEE Transactions on Nuclear Science

    6 publications · 168 citations

    6

    h-index

  4. Journal of Antimicrobial Chemotherapy

    JAC · 4 publications · 100 citations

    4

    h-index

  5. European Journal of Immunology

    EJI · 4 publications · 245 citations

    4

    h-index

1–5