Concepedia

Hepatic Lipase Function

Hepatic Lipase Function is a biochemical process mediated by the hepatic lipase enzyme, synthesized primarily in hepatocytes, that catalyzes the hydrolysis of triglycerides and phospholipids in remnant lipoproteins and high-density lipoproteins, thereby facilitating lipoprotein remodeling and influencing cholesterol ester redistribution in the final stages of lipoprotein metabolism.

1K

Publications

60.1K

Citations

4K

Authors

963

Institutions

Publications per year

2017–2026

53

Parents

Publications

1K

Remnant lipoprotein metabolism: key pathways involving cell-surface heparan sulfate proteoglycans and apolipoprotein E

Robert W. Mahley, Zhong-Sheng Ji · Journal of Lipid Research · 1999 · 689 citations · Full text

, , +17

A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis

Shaoqing He, Christopher McPhaul, John Li et al. · Journal of Biological Chemistry · 2009 · 600 citations · Full text

, , +17

Postprandial lipoprotein metabolism in normolipidemic men with and without coronary artery disease.

Pieter H.E. Groot, W A van Stiphout, X. H. Krauss et al. · Arteriosclerosis and Thrombosis A Journal of Vascular Biology · 1991 · 532 citations

, , +17

Human Lipoprotein Lipase Complementary DNA Sequence

Karen L. Wion, Todd G. Kirchgessner, Aldons J. Lusis et al. · Science · 1987 · 481 citations

, , +16

Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene ( <i>LIPC</i> )

Benjamin M. Neale, Jesen Fagerness, Robyn Reynolds et al. · Proceedings of the National Academy of Sciences · 2010 · 451 citations · Full text

, , +17

1–5 of 1K

Authors

4K

  1. HJ
    Hans Jansen

    Erasmus University Rotterdam, Netherlands

    40 publications · 2.5K citations

    27

    h-index

  2. JD
    John D. Brunzell

    University of Washington, United States

    25 publications · 2.8K citations

    25

    h-index

  3. EA
    Esko A. Nikkilä

    University of Helsinki, Finland

    25 publications · 2.5K citations

    23

    h-index

  4. TO
    Thomas Olivecrona

    Umeå University, Sweden

    27 publications · 1.5K citations

    22

    h-index

  5. CE
    Christian Ehnholm

    Institute for Molecular Medicine Finland, Finland

    27 publications · 1.9K citations

    22

    h-index

1–5 of 4K

Institutions

963

  1. University of Helsinki

    Helsinki, Finland

    33 h-index

    174 publications

    13.6K citations

  2. Erasmus University Rotterdam

    Rotterdam, The Netherlands

    30 h-index

    140 publications

    11.2K citations

  3. University of Washington

    Seattle, United States

    28 h-index

    127 publications

    12K citations

  4. Umeå University

    Umeå, Sweden

    25 h-index

    94 publications

    5.4K citations

  5. National Institutes of Health

    Bethesda, United States

    24 h-index

    114 publications

    11.1K citations

  6. National Heart Lung and Blood Institute

    Bethesda, United States

    24 h-index

    131 publications

    10.5K citations

  7. Inserm

    Paris, France

    23 h-index

    201 publications

    10.7K citations

  8. Cornell University

    Ithaca, United States

    20 h-index

    71 publications

    4.9K citations

1–8 of 963

Venues

  1. Journal of Lipid Research

    JLR · 114 publications · 7.6K citations

    53

    h-index

  2. Journal of Biological Chemistry

    JBC · 54 publications · 4.9K citations

    39

    h-index

  3. Atherosclerosis

    51 publications · 3K citations

    31

    h-index

  4. 31

    h-index

  5. Arteriosclerosis Thrombosis and Vascular Biology

    35 publications · 2.4K citations

    30

    h-index

1–5