Concepedia

Hepatic Function Adjustment

Hepatic Function Adjustment is a pharmacokinetic modeling method that modifies drug dosing parameters in geriatric populations based on quantified impairments in liver function to ensure therapeutic efficacy and safety during steady-state monitoring.

29

Publications

1.1K

Citations

197

Authors

86

Institutions

Publications per year

2017–2026

4

Parents

Publications

29

Relationship between baseline hepatic status and outcome, and effect of sorafenib on liver function: SHARP trial subanalyses

Jean‐Luc Raoul, Jordi Bruix, Tim F. Greten et al. · Journal of Hepatology · 2012 · 120 citations

, , +13

Doxorubicin (75 mg/m2) for hepatocellular carcinoma: clinical and pharmacokinetic results.

Chlebowski Rt, A Brzechwa-Adjukiewicz, Ann Cowden et al. · PubMed · 1984 · 114 citations

, , +17

TREATMENT OF SCHIZOPHRENIC REACTIONS WITH PHENOTHIAZINE DERIVATIVES

Jesse F. Casey, Julian J. Lasky, C. James Klett et al. · American Journal of Psychiatry · 1960 · 114 citations

, , +17

Effects of hepatic function on vancomycin clinical pharmacology

N Brown, D H Ho, K L Fong et al. · Antimicrobial Agents and Chemotherapy · 1983 · 73 citations · Full text

, , +17

<scp>CYP3A</scp> activity in severe liver cirrhosis correlates with <scp>C</scp>hild–<scp>P</scp>ugh and model for end‐stage liver disease (<scp>MELD</scp>) scores

Albader Albarmawi, David Czock, Annika Gauss et al. · British Journal of Clinical Pharmacology · 2013 · 61 citations · Full text

, , +17

1–5 of 29

Authors

197

  1. MT
    Masaji Tani

    Wakayama Medical University, Japan

    1 publications · 29 citations

    1

    h-index

  2. JS
    Julia Sealock

    Vanderbilt University Medical Center, United States

    1 publications · 33 citations

    1

    h-index

  3. SK
    Shoji Kubo

    Osaka City University, Japan

    1 publications · 10 citations

    1

    h-index

  4. DV
    D. Voliotis

    Bayer (United States), United States

    1 publications · 120 citations

    1

    h-index

  5. CR
    Chlebowski Rt

    UCLA Medical Center, United States

    1 publications · 114 citations

    1

    h-index

1–5 of 197

Institutions

86

  1. The University of Texas at San Antonio Health Science Center

    San Antonio, United States

    2 h-index

    7 publications

    212 citations

  2. Johns Hopkins University

    Baltimore, United States

    2 h-index

    4 publications

    192 citations

  3. Université Paris Cité

    Paris, France

    2 h-index

    9 publications

    108 citations

  4. Inserm

    Paris, France

    2 h-index

    5 publications

    168 citations

  5. Hôpital Cochin

    Paris, France

    1 h-index

    4 publications

    48 citations

  6. Charité - Universitätsmedizin Berlin

    Berlin, Germany

    1 h-index

    1 publications

    120 citations

  7. AHEPA University Hospital

    Thessaloniki, Greece

    1 h-index

    1 publications

    120 citations

  8. Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas

    Madrid, Spain

    1 h-index

    2 publications

    240 citations

1–8 of 86

Venues

  1. International Journal of STD & AIDS

    2 publications · 53 citations

    2

    h-index

  2. Journal of Hepatology

    2 publications · 159 citations

    2

    h-index

  3. Antimicrobial Agents and Chemotherapy

    AAC · 2 publications · 90 citations

    2

    h-index

  4. JAMA Surgery

    1 publications · 33 citations

    1

    h-index

  5. PubMed

    Repository · 1 publications · 114 citations

    1

    h-index

1–5