Concepedia

Hepatic Endoderm Patterning

Hepatic Endoderm Patterning is a developmental biological process that specifies the spatial and temporal differentiation of foregut endodermal cells into hepatic fate through localized signaling gradients and transcriptional regulation.

18

Publications

3.1K

Citations

106

Authors

47

Institutions

Publications per year

2017–2026

2

Parents

Publications

18

Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm

Jennifer M Rossi, N. Ray Dunn, Brigid L.M. Hogan et al. · Genes & Development · 2001 · 639 citations · Full text

, , +17

The homeobox gene <i>Hex</i> is required in definitive endodermal tissues for normal forebrain, liver and thyroid formation

Juan Pedro Martı́nez-Barberá, Melanie Clements, Paul Q. Thomas et al. · Development · 2000 · 474 citations

, , +15

BMP-4 is required for hepatic specification of mouse embryonic stem cell–derived definitive endoderm

Valerie Gouon–Evans, Lise Boussemart, Paul Gadue et al. · Nature Biotechnology · 2006 · 436 citations

, , +16

Highly efficient differentiation of hESCs to functional hepatic endoderm requires ActivinA and Wnt3a signaling

David C. Hay, Judy Fletcher, Catherine Payne et al. · Proceedings of the National Academy of Sciences · 2008 · 430 citations · Full text

, , +17

Hex homeobox gene controls the transition of the endoderm to a pseudostratified, cell emergent epithelium for liver bud development

Roque Bort, Massimo Signore, Kimberly D. Tremblay et al. · Developmental Biology · 2005 · 281 citations

, , +16

1–5 of 18

Authors

106

  1. KS
    Kenneth S. Zaret

    Fox Chase Cancer Center, United States

    3 publications · 1.1K citations

    3

    h-index

  2. GK
    Gordon Keller

    University Health Network, Canada

    3 publications · 546 citations

    3

    h-index

  3. KD
    Kimberly D. Tremblay

    University of Massachusetts Amherst, United States

    3 publications · 459 citations

    3

    h-index

  4. VG
    Valerie Gouon–Evans

    Icahn School of Medicine at Mount Sinai, United States

    3 publications · 517 citations

    3

    h-index

  5. JP
    Juan Pedro Martı́nez-Barberá

    University College London, United Kingdom

    2 publications · 755 citations

    2

    h-index

1–5 of 106

Institutions

47

  1. Fox Chase Cancer Center

    Philadelphia, United States

    3 h-index

    10 publications

    3.9K citations

  2. Icahn School of Medicine at Mount Sinai

    New York, United States

    3 h-index

    13 publications

    2K citations

  3. University of Edinburgh

    Edinburgh, United Kingdom

    2 h-index

    19 publications

    6.6K citations

  4. University Health Network

    Toronto, Canada

    2 h-index

    3 publications

    154 citations

  5. Nara Medical University

    Kashihara-shi, Japan

    2 h-index

    8 publications

    744 citations

  6. Johnson & Johnson (Brazil)

    São Paulo, Brazil

    1 h-index

    1 publications

    430 citations

  7. Brown University

    Providence, United States

    1 h-index

    4 publications

    2.6K citations

  8. Vanderbilt University Medical Center

    Nashville, United States

    1 h-index

    4 publications

    2.6K citations

1–8 of 47

Venues

  1. Developmental Cell

    3 publications · 339 citations

    3

    h-index

  2. Development

    2 publications · 562 citations

    2

    h-index

  3. Hepatology

    2 publications · 69 citations

    2

    h-index

  4. Stem Cell Research

    1 publications · 15 citations

    1

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 1 publications · 430 citations

    1

    h-index

1–5