Concepedia

Hemidesmosome Defects

Hemidesmosome Defects is a structural pathology characterized by abnormalities in hemidesmosomes, the specialized anchoring complexes that mediate epithelial cell adhesion to the basement membrane, leading to compromised dermal-epidermal integrity and blister formation in the context of epidermolysis bullosa.

67

Publications

4.8K

Citations

303

Authors

143

Institutions

Publications per year

2017–2026

4

Parents

Publications

67

Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survival.

James J. Dowling, Q C Yu, Elaine Fuchs · The Journal of Cell Biology · 1996 · 502 citations · Full text

, , +13

Conditional Ablation of β1 Integrin in Skin

S. Raghavan, Christoph Bauer, Gina Mundschau et al. · The Journal of Cell Biology · 2000 · 389 citations · Full text

, , +15

Targeted inactivation of plectin reveals essential function in maintaining the integrity of skin, muscle, and heart cytoarchitecture

Kerstin Andrä, Hans Lassmann, Reginald E. Bittner et al. · Genes & Development · 1997 · 334 citations · Full text

, , +17

Defective expression of plectin/HD1 in epidermolysis bullosa simplex with muscular dystrophy.

Yannick Gache, Stéphane Chavanas, J.‐P. Lacour et al. · Journal of Clinical Investigation · 1996 · 229 citations · Full text

, , +17

Hemidesmosome Formation Is Initiated by the β4 Integrin Subunit, Requires Complex Formation of β4 and HD1/Plectin, and Involves a Direct Interaction between β4 and the Bullous Pemphigoid Antigen 180

Roel Q.J. Schaapveld, Luca Borradori, Dirk Geerts et al. · The Journal of Cell Biology · 1998 · 183 citations · Full text

, , +14

1–5 of 67

Authors

303

  1. GM
    Guerrino Meneguzzi

    Inserm, France

    8 publications · 915 citations

    8

    h-index

  2. RA
    Robin A.J. Eady

    St Thomas' Hospital, United Kingdom

    6 publications · 304 citations

    6

    h-index

  3. JU
    Jouni Uitto

    Thomas Jefferson University, United States

    6 publications · 401 citations

    6

    h-index

  4. AS
    Arnoud Sonnenberg

    The Netherlands Cancer Institute, Netherlands

    6 publications · 518 citations

    6

    h-index

  5. GW
    Gerhard Wiche

    University of Vienna, Austria

    5 publications · 779 citations

    5

    h-index

1–5 of 303

Institutions

143

  1. Inserm

    Paris, France

    10 h-index

    33 publications

    3K citations

  2. Jefferson College

    Hillsboro, United States

    6 h-index

    8 publications

    832 citations

  3. The Netherlands Cancer Institute

    Amsterdam, The Netherlands

    6 h-index

    34 publications

    3.5K citations

  4. Jefferson Institute

    Washington, United States

    5 h-index

    11 publications

    1.5K citations

  5. St Thomas' Hospital

    London, United Kingdom

    5 h-index

    16 publications

    1.3K citations

  6. Thomas Jefferson University

    Philadelphia, United States

    5 h-index

    11 publications

    1.5K citations

  7. Vienna Biocenter

    Vienna, Austria

    3 h-index

    16 publications

    3.3K citations

  8. Hôpital Pasteur

    Nice, France

    3 h-index

    4 publications

    566 citations

1–8 of 143

Venues

  1. British Journal of Dermatology

    6 publications · 300 citations

    6

    h-index

  2. Journal of Investigative Dermatology

    JID · 5 publications · 281 citations

    5

    h-index

  3. PubMed

    Repository · 4 publications · 126 citations

    4

    h-index

  4. Archives of Dermatology

    3 publications · 161 citations

    3

    h-index

  5. The Journal of Cell Biology

    JCB · 3 publications · 1.1K citations

    3

    h-index

1–5