Concepedia

Heme Sensing

Heme Sensing is a biochemical regulatory mechanism that detects intracellular heme concentrations and modulates gene expression or cellular processes in response to heme availability, distinguishing it from other metabolic sensing pathways by its specific molecular recognition of heme as a signaling ligand.

211

Publications

11.6K

Citations

856

Authors

278

Institutions

Publications per year

2017–2026

46

Parents

Publications

211

Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease

John D. Belcher, Chunsheng Chen, Julia Nguyen et al. · Blood · 2013 · 689 citations · Full text

, , +10

NPAS2: A Gas-Responsive Transcription Factor

Elhadji M. Dioum, Jared Rutter, Jason R. Tuckerman et al. · Science · 2002 · 438 citations

, , +16

Structure of a biological oxygen sensor: A new mechanism for heme-driven signal transduction

Weimin Gong, Bing Hao, Sheref S. Mansy et al. · Proceedings of the National Academy of Sciences · 1998 · 359 citations · Full text

, , +17

Heme Induces Ubiquitination and Degradation of the Transcription Factor Bach1

Yukari Zenke-Kawasaki, Yoshihiro Dohi, Yasutake Katoh et al. · Molecular and Cellular Biology · 2007 · 340 citations · Full text

, , +13

Biological signaling by carbon monoxide and carbon monoxide-releasing molecules

Roberto Motterlini, Roberta Foresti · American Journal of Physiology-Cell Physiology · 2017 · 245 citations

, , +17

1–5 of 211

Authors

856

  1. TS
    Tôru Shimizu

    Tohoku University, Japan

    18 publications · 606 citations

    13

    h-index

  2. UL
    Ursula Liebl

    École Polytechnique, France

    11 publications · 347 citations

    11

    h-index

  3. MH
    Marten H. Vos

    École Polytechnique, France

    11 publications · 347 citations

    11

    h-index

  4. SA
    Shigetoshi Aono

    National Institutes of Natural Sciences, Japan

    11 publications · 412 citations

    11

    h-index

  5. MG
    Marie‐Alda Gilles‐Gonzalez

    The University of Texas Southwestern Medical Center, United States

    10 publications · 1.6K citations

    10

    h-index

1–5 of 856

Institutions

278

  1. Tohoku University

    Sendai, Japan

    15 h-index

    71 publications

    5.6K citations

  2. Inserm

    Paris, France

    14 h-index

    80 publications

    2.9K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    14 h-index

    62 publications

    2K citations

  4. École Polytechnique

    Palaiseau, France

    11 h-index

    57 publications

    1.9K citations

  5. National Institutes of Natural Sciences

    Tokyo, Japan

    11 h-index

    42 publications

    1.5K citations

  6. Okazaki Institute for Integrative Bioscience

    Okazaki, Japan

    10 h-index

    40 publications

    1.4K citations

  7. Charles University

    Prague, Czechia

    8 h-index

    43 publications

    808 citations

  8. The Ohio State University

    Columbus, United States

    8 h-index

    26 publications

    5.2K citations

1–8 of 278

Venues

  1. Biochemistry

    27 publications · 1.9K citations

    25

    h-index

  2. Journal of Biological Chemistry

    JBC · 30 publications · 1.5K citations

    23

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 15 publications · 1.3K citations

    15

    h-index

  4. Journal of Bacteriology

    JB · 10 publications · 576 citations

    10

    h-index

  5. Infection and Immunity

    IAI · 9 publications · 599 citations

    9

    h-index

1–5