Concepedia

Helicase-mediated Initiation

Helicase-Mediated Initiation is a molecular mechanism in the initiation phase of protein translation wherein the unwinding of secondary structure in mRNA is catalyzed by RNA helicases to facilitate ribosomal scanning and start codon recognition.

44

Publications

4K

Citations

185

Authors

82

Institutions

Publications per year

2017–2026

4

Parents

Publications

44

Mutational analysis of a DEAD box RNA helicase: the mammalian translation initiation factor eIF‐4A.

Arnim Pause, Nahum Sonenberg · The EMBO Journal · 1992 · 619 citations · Full text

, , +16

The Structural Mechanism of Translocation and Helicase Activity in T7 RNA Polymerase

Y. Whitney Yin, Thomas A. Steitz · Cell · 2004 · 331 citations · Full text

, , +16

Biochemical and Kinetic Characterization of the RNA Helicase Activity of Eukaryotic Initiation Factor 4A

George W. Rogers, Nancy J. Richter, William C. Merrick · Journal of Biological Chemistry · 1999 · 330 citations · Full text

, , +11

Topology and Regulation of the Human eIF4A/4G/4H Helicase Complex in Translation Initiation

Assen Marintchev, Katherine A. Edmonds, Boriana Marintcheva et al. · Cell · 2009 · 221 citations · Full text

, , +14

RNA Helicase A Interacts with RISC in Human Cells and Functions in RISC Loading

G. Brett Robb, Tariq M. Rana · Molecular Cell · 2007 · 220 citations · Full text

, , +14

1–5 of 44

Authors

185

  1. NS
    Nahum Sonenberg

    McGill University, Canada

    6 publications · 1.1K citations

    6

    h-index

  2. AP
    Arnim Pause

    McGill University, Canada

    5 publications · 916 citations

    5

    h-index

  3. PL
    Patrick Linder

    University of Geneva, Switzerland

    4 publications · 307 citations

    4

    h-index

  4. UG
    Ulf‐Peter Guenther

    Charité - Universitätsmedizin Berlin, Germany

    2 publications · 258 citations

    2

    h-index

  5. SR
    Stefanie R. Schmid

    University of Basel, Switzerland

    2 publications · 138 citations

    2

    h-index

1–5 of 185

Institutions

82

  1. McGill University

    Montreal, Canada

    6 h-index

    16 publications

    2.4K citations

  2. Case Western Reserve University

    Cleveland, United States

    3 h-index

    15 publications

    2.5K citations

  3. University of California, Davis

    Davis, United States

    3 h-index

    7 publications

    332 citations

  4. University of Basel

    Basel, Switzerland

    2 h-index

    6 publications

    510 citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    4 publications

    214 citations

  6. University of California, Los Angeles

    Los Angeles, United States

    2 h-index

    2 publications

    118 citations

  7. University of Graz

    Graz, Austria

    2 h-index

    6 publications

    356 citations

  8. Howard Hughes Medical Institute

    Chevy Chase, United States

    2 h-index

    5 publications

    1.1K citations

1–8 of 82

Venues

  1. Nucleic Acids Research

    5 publications · 161 citations

    5

    h-index

  2. Molecular and Cellular Biology

    MCB · 5 publications · 277 citations

    5

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 4 publications · 304 citations

    4

    h-index

  4. Journal of Biological Chemistry

    JBC · 4 publications · 434 citations

    4

    h-index

  5. Journal of Molecular Biology

    JMB · 3 publications · 125 citations

    3

    h-index

1–5