Concepedia

Half-life Estimation

Half-Life Estimation is a pharmacokinetic analysis method that quantifies the time required for the plasma concentration of a drug to decrease by half during the elimination phase, specifically derived from the terminal slope of the concentration-time curve in noncompartmental analysis.

1.5K

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76.6K

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5.5K

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1.3K

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2017–2026

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Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

David D. Ho, Avidan U. Neumann, Alan S. Perelson et al. · Nature · 1995 · 4.3K citations

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HIV-1 Dynamics in Vivo: Virion Clearance Rate, Infected Cell Life-Span, and Viral Generation Time

Alan S. Perelson, Avidan U. Neumann, Martin Markowitz et al. · Science · 1996 · 3.5K citations

, , +16

Half-Life of Serum Elimination of Perfluorooctanesulfonate,Perfluorohexanesulfonate, and Perfluorooctanoate in Retired Fluorochemical Production Workers

Geary W. Olsen, Jean M. Burris, David J. Ehresman et al. · Environmental Health Perspectives · 2007 · 2K citations · Full text

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Estimation of the ED50 and Its Error by Means of Logarithmic-Probit Graph Paper.

Louis W. Miller, M. L. Tainter · Experimental Biology and Medicine · 1944 · 1.1K citations

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Tables for Convenient Calculation of Median-Effective Dose (LD 50 or ED 50 ) and Instructions in Their Use

Carrol S. Weil · Biometrics · 1952 · 1.1K citations

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Authors

5.5K

  1. SP
    S. Pommé

    European Commission, Belgium

    19 publications · 585 citations

    14

    h-index

  2. KK
    Karsten Kossert

    Physikalisch-Technische Bundesanstalt, Germany

    13 publications · 1.4K citations

    12

    h-index

  3. RV
    R. Van Ammel

    European Commission, Belgium

    12 publications · 347 citations

    12

    h-index

  4. DJ
    David J. Greenblatt

    Tufts University, United States

    9 publications · 702 citations

    9

    h-index

  5. JP
    J. Paepen

    European Commission, Belgium

    9 publications · 287 citations

    9

    h-index

1–5 of 5.5K

Institutions

1.3K

  1. European Commission

    Brussels, Belgium

    14 h-index

    75 publications

    2.3K citations

  2. Physikalisch-Technische Bundesanstalt

    Braunschweig, Germany

    13 h-index

    31 publications

    1.9K citations

  3. University of California, San Francisco

    San Francisco, United States

    12 h-index

    41 publications

    4.5K citations

  4. University of Toronto

    Toronto, Canada

    12 h-index

    36 publications

    1.8K citations

  5. Uppsala University

    Uppsala, Sweden

    11 h-index

    14 publications

    485 citations

  6. Vanderbilt University

    Nashville, United States

    11 h-index

    36 publications

    1.6K citations

  7. Karolinska Institutet

    Stockholm, Sweden

    11 h-index

    30 publications

    1.1K citations

  8. Pfizer (United States)

    New York, United States

    11 h-index

    56 publications

    7.2K citations

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Venues

  1. Clinical Pharmacology & Therapeutics

    CPT · 67 publications · 4.6K citations

    40

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  2. PubMed

    Repository · 135 publications · 4.4K citations

    36

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  3. British Journal of Clinical Pharmacology

    BJCP · 49 publications · 2.3K citations

    27

    h-index

  4. Applied Radiation and Isotopes

    50 publications · 1.5K citations

    23

    h-index

  5. Antimicrobial Agents and Chemotherapy

    AAC · 32 publications · 1.9K citations

    22

    h-index

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