Concepedia

Group Sequential Trials

Group Sequential Trials is a statistical methodology in clinical and experimental research that belongs to the class of sequential testing procedures, distinguished by its pre-specified interim analyses conducted at discrete time points to evaluate accumulating data and determine whether a study should be stopped early for efficacy, futility, or safety.

413

Publications

27.8K

Citations

934

Authors

432

Institutions

Publications per year

2017–2026

42

Variants

Group Sequential Designs

Parents

Publications

413

Group sequential methods in the design and analysis of clinical trials

Stuart Pocock · Biometrika · 1977 · 1.8K citations

, , +13

Design and Analysis of Group-Randomized Trials

Seema S. Sonnad · Medicine & Science in Sports & Exercise · 1999 · 1.1K citations

, , +16

Sequential Analysis, Tests and Confidence Intervals

Josef Schmee, David Siegmund · Technometrics · 1987 · 728 citations

, , +12

Group Sequential Methods with Applications to Clinical Trials

KyungMann Kim · Controlled Clinical Trials · 2001 · 713 citations

, , +11

Adaptive Sample Size Calculations in Group Sequential Trials

Walter Lehmacher, Gernot Wassmer · Biometrics · 1999 · 604 citations · Full text

, , +15

1–5 of 413

Authors

934

  1. DL
    David L. DeMets

    University of Wisconsin–Madison, United States

    16 publications · 1.5K citations

    15

    h-index

  2. AA
    Anastasios A. Tsiatis

    North Carolina State University, United States

    15 publications · 1.5K citations

    14

    h-index

  3. SS
    Scott S. Emerson

    University of Washington, United States

    19 publications · 678 citations

    14

    h-index

  4. CJ
    Christopher Jennison

    University of Bath, United Kingdom

    13 publications · 1K citations

    13

    h-index

  5. CR
    Cyrus R. Mehta

    Cytel (United States), United States

    11 publications · 909 citations

    11

    h-index

1–5 of 934

Institutions

432

  1. Harvard University

    Cambridge, United States

    19 h-index

    28 publications

    1.8K citations

  2. University of Wisconsin–Madison

    Madison, United States

    18 h-index

    26 publications

    3K citations

  3. Cancer Research And Biostatistics

    Seattle, United States

    18 h-index

    30 publications

    1.3K citations

  4. University of Washington

    Seattle, United States

    16 h-index

    34 publications

    1.3K citations

  5. The University of Texas MD Anderson Cancer Center

    Houston, United States

    12 h-index

    27 publications

    1.6K citations

  6. University of Bath

    Bath, United Kingdom

    10 h-index

    11 publications

    901 citations

  7. MRC Biostatistics Unit

    Cambridge, United Kingdom

    10 h-index

    13 publications

    505 citations

  8. University of Florida

    Gainesville, United States

    10 h-index

    16 publications

    462 citations

1–8 of 432

Venues

  1. Biometrics

    61 publications · 5.4K citations

    35

    h-index

  2. Statistics in Medicine

    71 publications · 4.4K citations

    33

    h-index

  3. Biometrika

    31 publications · 3.8K citations

    24

    h-index

  4. Journal of Biopharmaceutical Statistics

    JBS · 20 publications · 541 citations

    15

    h-index

  5. Journal of the American Statistical Association

    14 publications · 970 citations

    13

    h-index

1–5