Concepedia

Glutamate Hypothesis

The Glutamate Hypothesis is a neurobiological theory proposing that dysregulation of glutamatergic neurotransmission, particularly through N-methyl-D-aspartate (NMDA) receptors, underlies the pathophysiology of psychotic disorders.

59

Publications

4.6K

Citations

283

Authors

123

Institutions

Publications per year

2017–2026

9

Parents

Publications

59

Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia

J.S. Kim, H. H. Kornhuber, W. Schmid‐Burgk et al. · Neuroscience Letters · 1980 · 698 citations

, , +14

Imaging Patients with Psychosis and a Mouse Model Establishes a Spreading Pattern of Hippocampal Dysfunction and Implicates Glutamate as a Driver

Scott Schobel, Nashid H. Chaudhury, Usman Khan et al. · Neuron · 2013 · 561 citations · Full text

, , +17

A “Glutamatergic Hypothesis” of Schizophrenia

Stephen I. Deutsch, John Mastropaolo, Barbara L. Schwartz et al. · Clinical Neuropharmacology · 1989 · 267 citations

, , +17

Negative schizophrenic symptomatology and the PCP (phencyclidine) model of schizophrenia.

D. Javitt · PubMed · 1987 · 241 citations

, , +17

Psychological effects of ketamine in healthy volunteers

Edith Pomarol‐Clotet, G.D. Honey, Graham K. Murray et al. · The British Journal of Psychiatry · 2006 · 207 citations · Full text

, , +14

1–5 of 59

Authors

283

  1. EG
    Edna Grünblatt

    University of Zurich, Switzerland

    2 publications · 34 citations

    2

    h-index

  2. KH
    Kenji Hashimoto

    Center for Forensic Mental Health, Chiba University, Japan

    2 publications · 131 citations

    2

    h-index

  3. PR
    Philip R. Corlett

    Yale University, United States

    2 publications · 223 citations

    2

    h-index

  4. MI
    Masaomi Iyo

    Chiba University, Japan

    2 publications · 131 citations

    2

    h-index

  5. PC
    Paul C. Fletcher

    University of Cambridge, United Kingdom

    2 publications · 332 citations

    2

    h-index

1–5 of 283

Institutions

123

  1. Charité - Universitätsmedizin Berlin

    Berlin, Germany

    3 h-index

    13 publications

    678 citations

  2. Central Institute of Mental Health

    Mannheim, Germany

    3 h-index

    16 publications

    940 citations

  3. University of Würzburg

    Würzburg, Germany

    3 h-index

    14 publications

    307 citations

  4. ETH Zurich

    Zurich, Switzerland

    2 h-index

    6 publications

    96 citations

  5. University of Maryland, Baltimore

    Baltimore, United States

    2 h-index

    9 publications

    261 citations

  6. Addenbrooke's Hospital

    Cambridge, United Kingdom

    2 h-index

    3 publications

    539 citations

  7. University of Cambridge

    Cambridge, United Kingdom

    2 h-index

    6 publications

    1.2K citations

  8. University Hospital of Zurich

    Zurich, Switzerland

    2 h-index

    10 publications

    182 citations

1–8 of 123

Venues

  1. PubMed

    Repository · 10 publications · 629 citations

    10

    h-index

  2. Biological Psychiatry

    2 publications · 190 citations

    2

    h-index

  3. Schizophrenia Research

    2 publications · 135 citations

    2

    h-index

  4. Schizophrenia Bulletin

    2 publications · 149 citations

    2

    h-index

  5. Clinical Neuropharmacology

    1 publications · 267 citations

    1

    h-index

1–5