Concepedia

Glucagon Biosynthesis

Glucagon Biosynthesis is the post-translational processing of proglucagon within pancreatic alpha cells that selectively cleaves and modifies the precursor polypeptide to yield the mature 29-amino-acid peptide hormone glucagon.

288

Publications

16.1K

Citations

1.1K

Authors

330

Institutions

Publications per year

2017–2026

15

Parents

Publications

288

Human adipose tissue-derived mesenchymal stem cells differentiate into insulin, somatostatin, and glucagon expressing cells

Katharina Timper, Dalma Seboek, Michael Eberhardt et al. · Biochemical and Biophysical Research Communications · 2006 · 449 citations

, , +14

TCF-4 Mediates Cell Type-specific Regulation of Proglucagon Gene Expression by β-Catenin and Glycogen Synthase Kinase-3β

Fenghua Yi, Patricia L. Brubaker, Tianru Jin · Journal of Biological Chemistry · 2004 · 411 citations · Full text

, , +17

Activation of proglucagon gene transcription by protein kinase-A in a novel mouse enteroendocrine cell line.

Daniel J. Drucker, Tianru Jin, T A Young et al. · Molecular Endocrinology · 1994 · 286 citations · Full text

, , +16

Pancreatic preproglucagon cDNA contains two glucagon-related coding sequences arranged in tandem.

P. Kay Lund, R H Goodman, P C Dee et al. · Proceedings of the National Academy of Sciences · 1982 · 282 citations

, , +15

Glucagon gene expression in vertebrate brain.

Daniel J. Drucker · Journal of Biological Chemistry · 1988 · 262 citations · Full text

, , +14

1–5 of 288

Authors

1.1K

  1. DJ
    Daniel J. Drucker

    University of Toronto, Canada

    13 publications · 1.5K citations

    13

    h-index

  2. JF
    Joel F. Habener

    Massachusetts General Hospital, United States

    11 publications · 1.3K citations

    11

    h-index

  3. JP
    Jacques Philippé

    University Hospital of Geneva, Switzerland

    9 publications · 342 citations

    9

    h-index

  4. JJ
    Jens J. Holst

    University of Copenhagen, Denmark

    9 publications · 425 citations

    9

    h-index

  5. PL
    Patricia L. Brubaker

    University of Toronto, Canada

    8 publications · 946 citations

    8

    h-index

1–5 of 1.1K

Institutions

330

  1. University of Toronto

    Toronto, Canada

    19 h-index

    62 publications

    6.1K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    18 h-index

    59 publications

    7.1K citations

  3. University of Geneva

    Geneva, Switzerland

    11 h-index

    37 publications

    1.8K citations

  4. Toronto General Hospital

    Toronto, Canada

    11 h-index

    27 publications

    2.3K citations

  5. Harvard University

    Cambridge, United States

    11 h-index

    42 publications

    4.3K citations

  6. Massachusetts General Hospital

    Boston, United States

    11 h-index

    44 publications

    4.1K citations

  7. University of Copenhagen

    Copenhagen, Denmark

    11 h-index

    33 publications

    1.5K citations

  8. University of Chicago

    Chicago, United States

    9 h-index

    29 publications

    2.5K citations

1–8 of 330

Venues

  1. Endocrinology

    36 publications · 1.9K citations

    26

    h-index

  2. Journal of Biological Chemistry

    JBC · 18 publications · 2.4K citations

    17

    h-index

  3. Diabetes

    21 publications · 1.1K citations

    16

    h-index

  4. Diabetologia

    13 publications · 536 citations

    12

    h-index

  5. Journal of Clinical Investigation

    JCI · 11 publications · 918 citations

    11

    h-index

1–5