Concepedia

Germline Mutation Rate

Germline Mutation Rate is a genetic metric that quantifies the frequency at which de novo mutations arise in the germline cells per generation or per base pair per generation, distinguishing it from somatic mutation rates by its exclusive focus on heritable genetic changes transmitted to offspring.

171

Publications

12.4K

Citations

962

Authors

398

Institutions

Publications per year

2017–2026

54

Variants

Germline Mutation Frequency

Parents

Publications

171

Rate, molecular spectrum, and consequences of human mutation

Michael Lynch · Proceedings of the National Academy of Sciences · 2010 · 834 citations · Full text

, , +17

Timing, rates and spectra of human germline mutation

Raheleh Rahbari, Arthur Wüster, Sarah Lindsay et al. · Nature Genetics · 2015 · 729 citations · Full text

, , +12

Parental influence on human germline de novo mutations in 1,548 trios from Iceland

Hákon Jónsson, Patrick Sulem, Birte Kehr et al. · Nature · 2017 · 651 citations

, , +13

PERSPECTIVE: SPONTANEOUS DELETERIOUS MUTATION

Michael Lynch, Jeffrey L. Blanchard, David Houle et al. · Evolution · 1999 · 475 citations

, , +13

Differences between germline and somatic mutation rates in humans and mice

Brandon Milholland, Xiao Dong, Lei Zhang et al. · Nature Communications · 2017 · 443 citations · Full text

, , +11

1–5 of 171

Authors

962

  1. YE
    Yuri E. Dubrova

    University of Leicester, United Kingdom

    8 publications · 274 citations

    8

    h-index

  2. MP
    Molly Przeworski

    Columbia University, United States

    8 publications · 514 citations

    8

    h-index

  3. ML
    Michael Lynch

    Indiana University Bloomington, United States

    8 publications · 1.8K citations

    8

    h-index

  4. PM
    Priya Moorjani

    Harvard University, United States

    6 publications · 327 citations

    6

    h-index

  5. ME
    Matthew E. Hurles

    Wellcome Sanger Institute, United Kingdom

    6 publications · 977 citations

    6

    h-index

1–5 of 962

Institutions

398

  1. University of Leicester

    Leicester, United Kingdom

    11 h-index

    33 publications

    1.3K citations

  2. Indiana University Bloomington

    Bloomington, United States

    11 h-index

    28 publications

    2.4K citations

  3. Columbia University

    New York, United States

    8 h-index

    20 publications

    1.1K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    7 h-index

    7 publications

    491 citations

  5. Wellcome Sanger Institute

    Cambridge, United Kingdom

    6 h-index

    44 publications

    7.5K citations

  6. Stanford University

    Stanford, United States

    5 h-index

    5 publications

    417 citations

  7. University of Southern California

    Los Angeles, United States

    5 h-index

    25 publications

    1.5K citations

  8. Arizona State University

    Tempe, United States

    5 h-index

    8 publications

    367 citations

1–8 of 398

Venues

  1. 10

    h-index

  2. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 8 publications · 135 citations

    8

    h-index

  3. Genetics

    8 publications · 540 citations

    8

    h-index

  4. Nature Communications

    7 publications · 1.1K citations

    7

    h-index

  5. Human Mutation

    6 publications · 211 citations

    6

    h-index

1–5