Concepedia

Gene Construct Design

Gene Construct Design is the systematic formulation of a recombinant DNA sequence, incorporating regulatory elements and coding regions, tailored for stable integration and functional expression in a target organism, distinguishing it from generic genetic engineering methods by its precise architectural planning and purpose-specific functionality.

58

Publications

2.3K

Citations

310

Authors

106

Institutions

Publications per year

2017–2026

20

Parents

Publications

58

Writing DNA with GenoCADTM

Michael J. Czar, Yizhi Cai, Jean Peccoud · Nucleic Acids Research · 2009 · 151 citations · Full text

, , +17

Automated design of thousands of nonrepetitive parts for engineering stable genetic systems

Ayaan Hossain, Eriberto Lopez, Sean M. Halper et al. · Nature Biotechnology · 2020 · 139 citations · Full text

, , +15

Expression of a partially deleted gene of human type II procollagen (COL2A1) in transgenic mice produces a chondrodysplasia.

Philipp Vandenberg, Jaspal S. Khillan, D.J. Prockop et al. · Proceedings of the National Academy of Sciences · 1991 · 133 citations

, , +15

Random circular permutation of genes and expressed polypeptide chains: application of the method to the catalytic chains of aspartate transcarbamoylase.

Roney Graf, H. K. Schachman · Proceedings of the National Academy of Sciences · 1996 · 95 citations

, , +14

A translational enhancer derived from tobacco mosaic virus is functionally equivalent to a Shine-Dalgarno sequence.

Daniel Gallie, Clarence I. Kado · Proceedings of the National Academy of Sciences · 1989 · 90 citations · Full text

, , +17

1–5 of 58

Authors

310

  1. JP
    Jean Peccoud

    Virginia Tech, United States

    4 publications · 309 citations

    4

    h-index

  2. YC
    Yizhi Cai

    University of Edinburgh, United Kingdom

    3 publications · 298 citations

    3

    h-index

  3. MW
    Mark Welch

    Menlo School, United States

    2 publications · 71 citations

    2

    h-index

  4. AV
    Alan Villalobos

    Menlo School, United States

    2 publications · 71 citations

    2

    h-index

  5. JM
    Jeremy Minshull

    ATUM (United States), United States

    2 publications · 71 citations

    2

    h-index

1–5 of 310

Institutions

106

  1. Virginia Tech

    Blacksburg, United States

    4 h-index

    14 publications

    1K citations

  2. University of California, Davis

    Davis, United States

    3 h-index

    5 publications

    376 citations

  3. Menlo School

    Atherton, United States

    2 h-index

    7 publications

    274 citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    13 publications

    463 citations

  5. University of Washington

    Seattle, United States

    2 h-index

    4 publications

    451 citations

  6. Newcastle University

    Newcastle upon Tyne, United Kingdom

    2 h-index

    7 publications

    198 citations

  7. National Research Centre on Plant Biotechnology

    New Delhi, India

    2 h-index

    8 publications

    196 citations

  8. Massachusetts Institute of Technology

    Cambridge, United States

    1 h-index

    1 publications

    18 citations

1–8 of 106

Venues

  1. Methods in enzymology on CD-ROM/Methods in enzymology

    Book series · 3 publications · 93 citations

    3

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 318 citations

    3

    h-index

  3. ACS Synthetic Biology

    3 publications · 86 citations

    3

    h-index

  4. Microbial Cell Factories

    3 publications · 96 citations

    3

    h-index

  5. Bioinformatics

    2 publications · 94 citations

    2

    h-index

1–5