Concepedia

Galactose Conjugation

Galactose Conjugation is a chemical modification strategy in oligonucleotide delivery wherein galactose molecules are covalently attached to oligonucleotides or their carriers to enable selective targeting of hepatocytes via the asialoglycoprotein receptor-mediated endocytosis pathway.

671

Publications

33.6K

Citations

2.9K

Authors

819

Institutions

Publications per year

2017–2026

64

Variants

Gal-conjugation

Parents

Publications

671

Biochemical Method for Inserting New Genetic Information into DNA of Simian Virus 40: Circular SV40 DNA Molecules Containing Lambda Phage Genes and the Galactose Operon of <i>Escherichia coli</i>

David A. Jackson, Robert H. Symons, Paul Berg · Proceedings of the National Academy of Sciences · 1972 · 762 citations · Full text

, , +17

Anti-pig IgM antibodies in human serum react predominantly with Gal(alpha 1-3)Gal epitopes.

Mauro S. Sandrin, H Vaughan, Paul Dabkowski et al. · Proceedings of the National Academy of Sciences · 1993 · 610 citations · Full text

, , +16

The Leloir pathway: a mechanistic imperative for three enzymes to change the stereochemical configuration of a single carbon in galactose

Perry A. Frey · The FASEB Journal · 1996 · 472 citations

, , +17

The immobilized leukoagglutinin from the seeds of Maackia amurensis binds with high affinity to complex-type Asn-linked oligosaccharides containing terminal sialic acid-linked alpha-2,3 to penultimate galactose residues.

Wen‐Ching Wang, Richard D. Cummings · Journal of Biological Chemistry · 1988 · 455 citations · Full text

, , +17

Generalized Gangliosidosis: Beta-Galactosidase Deficiency

Shintaro Okada, John S. O’Brien · Science · 1968 · 430 citations

, , +15

1–5 of 671

Authors

2.9K

  1. EG
    Eric G. Berger

    University of Zurich, Switzerland

    6 publications · 160 citations

    6

    h-index

  2. TA
    Toshihiro Akaike

    Tokyo Institute of Technology, Japan

    6 publications · 186 citations

    6

    h-index

  3. TA
    Toshihiro Akaike

    Tokyo Institute of Technology, Japan

    5 publications · 142 citations

    5

    h-index

  4. MH
    Mitsuru Hashida

    Kyoto University, Japan

    5 publications · 317 citations

    5

    h-index

  5. KF
    Kiyoshi Furukawa

    The University of Tokyo, Japan

    5 publications · 171 citations

    5

    h-index

1–5 of 2.9K

Institutions

819

  1. Harvard University

    Cambridge, United States

    16 h-index

    49 publications

    3.5K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    14 h-index

    69 publications

    3.7K citations

  3. Johns Hopkins University

    Baltimore, United States

    13 h-index

    44 publications

    3K citations

  4. Tokyo Institute of Technology

    Tokyo, Japan

    11 h-index

    27 publications

    829 citations

  5. Albert Einstein College of Medicine

    Bronx, United States

    8 h-index

    30 publications

    1.8K citations

  6. Nagoya University

    Nagoya, Japan

    8 h-index

    23 publications

    610 citations

  7. Inserm

    Paris, France

    7 h-index

    20 publications

    433 citations

  8. Brigham and Women's Hospital

    Boston, United States

    7 h-index

    21 publications

    1.6K citations

1–8 of 819

Venues

  1. Journal of Biological Chemistry

    JBC · 65 publications · 4K citations

    39

    h-index

  2. PubMed

    Repository · 26 publications · 932 citations

    19

    h-index

  3. Bioconjugate Chemistry

    19 publications · 1.9K citations

    18

    h-index

  4. European Journal of Biochemistry

    EJB · 23 publications · 1.1K citations

    17

    h-index

  5. Biochemical Journal

    BJ · 16 publications · 545 citations

    13

    h-index

1–5