Concepedia

Gaba-glutamine Cycle

The GABA-Glutamine Cycle is a neurochemical recycling process in which astrocyte-derived glutamine serves as a precursor for neuronal synthesis of gamma-aminobutyric acid (GABA), followed by subsequent reuptake of synaptically released GABA into glial cells and its reconversion to glutamine, thus maintaining the balance of inhibitory neurotransmission in the central nervous system.

60

Publications

4.9K

Citations

261

Authors

113

Institutions

Publications per year

2017–2026

18

Variants

Gaba-glutamine Shunt

Parents

Publications

60

The gut microbiome from patients with schizophrenia modulates the glutamate-glutamine-GABA cycle and schizophrenia-relevant behaviors in mice

Peng Zheng, Benhua Zeng, Meiling Liu et al. · Science Advances · 2019 · 709 citations · Full text

, , +17

SUBCELLULAR DISTRIBUTION OF THE ENZYMES OF THE GLUTAMIC ACID, GLUTAMINE AND γ‐AMINOBUTYRIC ACID CYCLES IN RAT BRAIN*

Leon Salganicoff, E. De Robertis · Journal of Neurochemistry · 1965 · 543 citations

, , +16

The contribution of GABA to glutamate/glutamine cycling and energy metabolism in the rat cortex <i>in vivo</i>

Anant B. Patel, Robin A. de Graaf, Graeme F. Mason et al. · Proceedings of the National Academy of Sciences · 2005 · 343 citations

, , +17

Astrocytic Control of Biosynthesis and Turnover of the Neurotransmitters Glutamate and GABA

Arne Schousboe, Lasse K. Bak, Helle S. Waagepetersen · Frontiers in Endocrinology · 2013 · 299 citations · Full text

, , +17

The Glutamate–Glutamine (GABA) Cycle: Importance of Late Postnatal Development and Potential Reciprocal Interactions between Biosynthesis and Degradation

Leif Hertz · Frontiers in Endocrinology · 2013 · 237 citations · Full text

, , +17

1–5 of 60

Authors

261

  1. AB
    Anant B. Patel

    Centre for Cellular and Molecular Biology, India

    7 publications · 637 citations

    7

    h-index

  2. KL
    Kevin L. Behar

    Yale University, United States

    6 publications · 610 citations

    6

    h-index

  3. DL
    Douglas L. Rothman

    Yale University, United States

    5 publications · 559 citations

    5

    h-index

  4. RA
    Robin A. de Graaf

    Yale University, United States

    4 publications · 451 citations

    4

    h-index

  5. AS
    Arne Schousboe

    University of Copenhagen, Denmark

    3 publications · 413 citations

    3

    h-index

1–5 of 261

Institutions

113

  1. Yale University

    New Haven, United States

    8 h-index

    30 publications

    3.5K citations

  2. University of Copenhagen

    Copenhagen, Denmark

    7 h-index

    20 publications

    2.4K citations

  3. Resonance Research (United States)

    Billerica, United States

    6 h-index

    24 publications

    2.8K citations

  4. Australian National University

    Canberra, Australia

    3 h-index

    4 publications

    426 citations

  5. Case Western Reserve University

    Cleveland, United States

    3 h-index

    6 publications

    189 citations

  6. Centre for Cellular and Molecular Biology

    Hyderabad, India

    3 h-index

    5 publications

    166 citations

  7. The Affiliated Yongchuan Hospital of Chongqing Medical University

    Chongqing, China

    2 h-index

    19 publications

    6.8K citations

  8. Chongqing Medical University

    Chongqing, China

    2 h-index

    22 publications

    9K citations

1–8 of 113

Venues

  1. Journal of Neurochemistry

    JNC · 9 publications · 1.1K citations

    9

    h-index

  2. Frontiers in Endocrinology

    4 publications · 739 citations

    4

    h-index

  3. Journal of Neuroscience Research

    JNR · 3 publications · 146 citations

    3

    h-index

  4. Brain Research

    3 publications · 162 citations

    3

    h-index

  5. Journal of Cerebral Blood Flow & Metabolism

    2 publications · 75 citations

    3

    h-index

1–5