Concepedia

G-quadruplex-protein Interactions

G-Quadruplex-Protein Interactions is a molecular recognition phenomenon in which a structured nucleic acid motif formed by guanine-rich sequences, known as a G-quadruplex, specifically associates with a protein partner through non-covalent interactions, thereby modulating biological processes such as gene expression, DNA replication, or telomere maintenance.

289

Publications

18.7K

Citations

1.4K

Authors

488

Institutions

Publications per year

2017–2026

144

Parents

Publications

289

G-quadruplex structures mark human regulatory chromatin

Robert Hänsel‐Hertsch, Dario Beraldi, Stefanie V. Lensing et al. · Nature Genetics · 2016 · 1K citations · Full text

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DNA Replication through G-Quadruplex Motifs Is Promoted by the Saccharomyces cerevisiae Pif1 DNA Helicase

Katrin Paeschke, John A. Capra, Virginia A. Zakian · Cell · 2011 · 573 citations · Full text

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Telomestatin, a Potent Telomerase Inhibitor That Interacts Quite Specifically with the Human Telomeric Intramolecular G-Quadruplex

Mu-Yong Kim, Hariprasad Vankayalapati, Kazuo Shin‐ya et al. · Journal of the American Chemical Society · 2002 · 515 citations

, , +17

Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter

Anh Tuân Phan, Vitaly Kuryavyi, Hai Yan Gaw et al. · Nature Chemical Biology · 2005 · 509 citations · Full text

, , +15

Unraveling cell type–specific and reprogrammable human replication origin signatures associated with G-quadruplex consensus motifs

Emilie Besnard, Amélie Babled, Laure Lapasset et al. · Nature Structural & Molecular Biology · 2012 · 442 citations

, , +15

1–5 of 289

Authors

1.4K

  1. SB
    Shankar Balasubramanian

    University of Cambridge, United Kingdom

    9 publications · 2.1K citations

    9

    h-index

  2. JM
    Jean‐Louis Mergny

    Inserm, France

    8 publications · 425 citations

    8

    h-index

  3. MT
    Marie‐Paule Teulade‐Fichou

    Centre National de la Recherche Scientifique, France

    6 publications · 323 citations

    6

    h-index

  4. JT
    Jia‐Heng Tan

    Sun Yat-sen University, China

    6 publications · 236 citations

    6

    h-index

  5. AT
    Anh Tuân Phan

    Nanyang Technological University, Singapore

    5 publications · 789 citations

    5

    h-index

1–5 of 1.4K

Institutions

488

  1. Inserm

    Paris, France

    18 h-index

    50 publications

    3.3K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    18 h-index

    71 publications

    4.4K citations

  3. Chinese Academy of Sciences

    Beijing, China

    16 h-index

    105 publications

    6K citations

  4. University of Chinese Academy of Sciences

    Beijing, China

    12 h-index

    38 publications

    1.6K citations

  5. University of Naples Federico II

    Naples, Italy

    10 h-index

    50 publications

    2.3K citations

  6. University of Cambridge

    Cambridge, United Kingdom

    9 h-index

    35 publications

    6.7K citations

  7. Beijing National Laboratory for Molecular Sciences

    Beijing, China

    9 h-index

    52 publications

    1.9K citations

  8. Université de Bordeaux

    Bordeaux, France

    8 h-index

    16 publications

    922 citations

1–8 of 488

Venues

  1. Nucleic Acids Research

    31 publications · 2.8K citations

    27

    h-index

  2. Chemical Communications

    ChemComm · 15 publications · 804 citations

    14

    h-index

  3. Biochemistry

    12 publications · 558 citations

    12

    h-index

  4. Journal of the American Chemical Society

    JACS · 11 publications · 1.5K citations

    11

    h-index

  5. Biochimie

    10 publications · 462 citations

    10

    h-index

1–5