Concepedia

G-quadruplex Unwinding

G-Quadruplex Unwinding is a molecular process in which stable four-stranded nucleic acid structures formed by guanine-rich sequences are disrupted or resolved into single-stranded DNA, typically mediated by helicase enzymes or chemical agents to facilitate essential genomic functions such as replication, transcription, and telomere maintenance.

66

Publications

6.6K

Citations

321

Authors

137

Institutions

Publications per year

2017–2026

26

Parents

Publications

66

FANCJ Helicase Defective in Fanconia Anemia and Breast Cancer Unwinds G-Quadruplex DNA To Defend Genomic Stability

Yuliang Wu, Kazuo Shin‐ya, Robert M. Brosh · Molecular and Cellular Biology · 2008 · 422 citations

, , +17

Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents

Daekyu Sun · Nucleic Acids Research · 2005 · 403 citations · Full text

, , +16

The Yeast Pif1 Helicase Prevents Genomic Instability Caused by G-Quadruplex-Forming CEB1 Sequences In Vivo

Cyril Ribeyre, Judith Lopes, Jean-Baptiste Boulé et al. · PLoS Genetics · 2009 · 362 citations · Full text

, , +16

G‐quadruplex‐induced instability during leading‐strand replication

Judith Lopes, Aurèle Piazza, Rodrigo Bermejo et al. · The EMBO Journal · 2011 · 333 citations · Full text

, , +14

Genomic distribution and functional analyses of potential G-quadruplex-forming sequences in Saccharomyces cerevisiae

Steven G. Hershman, Qijun Chen, Julia Y. Lee et al. · Nucleic Acids Research · 2007 · 279 citations · Full text

, , +17

1–5 of 66

Authors

321

  1. XX
    Xu‐Guang Xi

    Centre National de la Recherche Scientifique, France

    6 publications · 314 citations

    6

    h-index

  2. XH
    Xi‐Miao Hou

    Northwest A&F University, China

    5 publications · 266 citations

    5

    h-index

  3. SD
    Shuo‐Xing Dou

    Institute of Physics, China

    4 publications · 257 citations

    4

    h-index

  4. RM
    Robert M. Brosh

    National Institute on Aging, United States

    4 publications · 820 citations

    4

    h-index

  5. JB
    Jean-Baptiste Boulé

    Centre National de la Recherche Scientifique, France

    4 publications · 668 citations

    4

    h-index

1–5 of 321

Institutions

137

  1. Centre National de la Recherche Scientifique

    Paris, France

    15 h-index

    48 publications

    7.5K citations

  2. Inserm

    Paris, France

    7 h-index

    21 publications

    2.1K citations

  3. Chinese Academy of Sciences

    Beijing, China

    6 h-index

    19 publications

    1.8K citations

  4. Northwest A&F University

    Yangling, China

    6 h-index

    34 publications

    1.7K citations

  5. Institut Curie

    Paris, France

    5 h-index

    25 publications

    5.4K citations

  6. Laboratoire de Biologie et Pharmacologie Appliquée

    Cachan, France

    5 h-index

    6 publications

    294 citations

  7. Sorbonne Université

    Paris, France

    5 h-index

    27 publications

    5K citations

  8. Dynamique de l'information génétique : bases fondamentales et cancer

    Paris, France

    4 h-index

    21 publications

    4.7K citations

1–8 of 137

Venues

  1. Nucleic Acids Research

    18 publications · 2.3K citations

    17

    h-index

  2. Journal of Biological Chemistry

    JBC · 9 publications · 846 citations

    9

    h-index

  3. Biochemistry

    4 publications · 198 citations

    4

    h-index

  4. Journal of the American Chemical Society

    JACS · 3 publications · 155 citations

    3

    h-index

  5. Biochemical Journal

    BJ · 3 publications · 242 citations

    3

    h-index

1–5