Concepedia

Functional Potency Assays

Functional Potency Assays is a class of bioanalytical methods that measure the biological activity of a therapeutic agent by assessing its ability to elicit a specific, quantifiable cellular or physiological response, thereby distinguishing it from binding or structural assays that do not evaluate functional activity.

52

Publications

3.6K

Citations

467

Authors

133

Institutions

Publications per year

2017–2026

15

Variants

Biological Potency Assays

Parents

Publications

52

International Society for Cellular Therapy perspective on immune functional assays for mesenchymal stromal cells as potency release criterion for advanced phase clinical trials

Jacques Galipeau, Mauro Krampera, John Barrett et al. · Cytotherapy · 2015 · 516 citations · Full text

, , +17

Pharmacological and immunohistochemical characterization of the APJ receptor and its endogenous ligand apelin

Andrew D. Medhurst, Carol A. Jennings, Melanie J. Robbins et al. · Journal of Neurochemistry · 2003 · 437 citations · Full text

, , +17

<i>N</i>-(2-Benzoylphenyl)-<scp>l</scp>-tyrosine PPARγ Agonists. 1. Discovery of a Novel Series of Potent Antihyperglycemic and Antihyperlipidemic Agents

Brad R. Henke, Steven G. Blanchard, Marcus F. Brackeen et al. · Journal of Medicinal Chemistry · 1998 · 301 citations · Full text

, , +10

A functional test identifies dopamine agonists selective for D3 versus D2 receptors

François Sautel, Daniel Lévesque, J.C. Schwartz et al. · Neuroreport · 1995 · 213 citations

, , +16

Optimization of Cellular Activity of G9a Inhibitors 7-Aminoalkoxy-quinazolines

Feng Liu, Dalia Baršytė-Lovejoy, Abdellah Allali‐Hassani et al. · Journal of Medicinal Chemistry · 2011 · 155 citations · Full text

, , +13

1–5 of 52

Authors

467

  1. DD
    Darı́o Doller

    Texas A&M University, United States

    2 publications · 151 citations

    2

    h-index

  2. RE
    Robert E. Widdop

    Monash University, Australia

    2 publications · 91 citations

    2

    h-index

  3. SB
    Sanja Bosnyak

    Monash University, Australia

    2 publications · 91 citations

    2

    h-index

  4. DE
    David E. Nichols

    Purdue University West Lafayette, United States

    2 publications · 170 citations

    2

    h-index

  5. AC
    Alan C. Foster

    Neurocrine Biosciences (United States), United States

    2 publications · 87 citations

    2

    h-index

1–5 of 467

Institutions

133

  1. Monash University

    Melbourne, Australia

    3 h-index

    34 publications

    1.7K citations

  2. National Institutes of Health

    Bethesda, United States

    3 h-index

    8 publications

    1K citations

  3. University of Wisconsin–Madison

    Madison, United States

    2 h-index

    2 publications

    557 citations

  4. Inserm

    Paris, France

    2 h-index

    3 publications

    1.2K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    3 publications

    1.1K citations

  6. Technische Universität Dresden

    Dresden, Germany

    2 h-index

    5 publications

    241 citations

  7. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    2 h-index

    9 publications

    1.2K citations

  8. Tulane University

    New Orleans, United States

    2 h-index

    7 publications

    594 citations

1–8 of 133

Venues

  1. Journal of Medicinal Chemistry

    11 publications · 993 citations

    11

    h-index

  2. Cytotherapy

    3 publications · 574 citations

    3

    h-index

  3. ACS Chemical Neuroscience

    2 publications · 94 citations

    2

    h-index

  4. SLAS DISCOVERY

    2 publications · 58 citations

    2

    h-index

  5. British Journal of Pharmacology

    BJP · 2 publications · 121 citations

    2

    h-index

1–5