Concepedia

Functional Genome Construction

Functional Genome Construction is a methodological framework within genome writing that enables the design and assembly of synthetic genomic sequences with predefined biological activities, distinguished by its integration of functional annotations and regulatory elements to ensure phenotypic expression in host organisms.

21

Publications

2.2K

Citations

204

Authors

70

Institutions

Publications per year

2017–2026

8

Parents

Publications

21

Functional genomic hypothesis generation and experimentation by a robot scientist

Ross D. King, Kenneth E. Whelan, Ffion Mair Jones et al. · Nature · 2004 · 660 citations · Full text

, , +7

A recombineering pipeline for functional genomics applied to Caenorhabditis elegans

Mihail Sarov, Susan Schneider, Andrei Pozniakovski et al. · Nature Methods · 2006 · 202 citations · Full text

, , +16

Regeneration of a functional RNA virus genome by recombination between deletion mutants and requirement for cowpea chlorotic mottle virus 3a and coat genes for systemic infection.

Robert W. Allison, C. Thompson, Paul Ahlquist · Proceedings of the National Academy of Sciences · 1990 · 194 citations

, , +14

Manipulating the Mouse Genome to Engineer Precise Functional Syntenic Replacements with Human Sequence

Helen A. C. Wallace, Fatima Marques-Kranc, Melville Richardson et al. · Cell · 2007 · 165 citations · Full text

, , +16

Characterization of nonprimate hepacivirus and construction of a functional molecular clone

Troels K. H. Scheel, Amit Kapoor, Eiko Nishiuchi et al. · Proceedings of the National Academy of Sciences · 2015 · 100 citations · Full text

, , +17

1–5 of 21

Authors

204

  1. LA
    Leslie A. Mitchell

    University of British Columbia, Canada

    2 publications · 127 citations

    2

    h-index

  2. MT
    Matthew T. Maurano

    New York University, United States

    2 publications · 127 citations

    2

    h-index

  3. MS
    Megan S. Hogan

    Institute for Systems Biology, United States

    2 publications · 127 citations

    2

    h-index

  4. JD
    Jef D. Boeke

    Johns Hopkins University, United States

    2 publications · 127 citations

    2

    h-index

  5. SP
    Sudarshan Pinglay

    NYU Langone Health, United States

    2 publications · 127 citations

    2

    h-index

1–5 of 204

Institutions

70

  1. Technische Universität Dresden

    Dresden, Germany

    2 h-index

    12 publications

    1.2K citations

  2. NYU Langone Health

    New York, United States

    2 h-index

    14 publications

    804 citations

  3. Institute for Systems Biology

    Seattle, United States

    2 h-index

    25 publications

    1.6K citations

  4. Zhejiang University

    Hangzhou, China

    2 h-index

    12 publications

    415 citations

  5. National Institute for Parasitic Diseases

    Shanghai, China

    1 h-index

    6 publications

    546 citations

  6. Chinese Academy of Medical Sciences & Peking Union Medical College

    Beijing, China

    1 h-index

    1 publications

    35 citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    1 h-index

    11 publications

    671 citations

  8. Tsinghua University

    Beijing, China

    1 h-index

    7 publications

    686 citations

1–8 of 70

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 366 citations

    3

    h-index

  2. PubMed

    Repository · 1 publications · 35 citations

    1

    h-index

  3. Bioresource Technology

    1 publications · 20 citations

    1

    h-index

  4. Journal of Virology

    JVI · 1 publications · 51 citations

    1

    h-index

  5. Nature

    1 publications · 660 citations

    1

    h-index

1–5