Concepedia

Fumarate Therapy

Fumarate Therapy is a pharmacotherapeutic approach in multiple sclerosis management that involves the use of fumarate esters, primarily dimethyl fumarate, to modulate the immune system and reduce neuroinflammation through activation of the Nrf2 antioxidant pathway.

335

Publications

19.9K

Citations

2.6K

Authors

809

Institutions

Publications per year

2017–2026

193

Parents

Publications

335

Placebo-Controlled Phase 3 Study of Oral BG-12 for Relapsing Multiple Sclerosis

Ralf Gold, Ludwig Kappos, Douglas L. Arnold et al. · New England Journal of Medicine · 2012 · 1.7K citations · Full text

, , +17

Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway

Ralf A. Linker, De-Hyung Lee, Sarah Ryan et al. · Brain · 2011 · 1.2K citations · Full text

, , +17

Succination inactivates gasdermin D and blocks pyroptosis

Fiachra Humphries, Liraz Shmuel-Galia, Natália Ketelut-Carneiro et al. · Science · 2020 · 655 citations · Full text

, , +17

Clemastine fumarate as a remyelinating therapy for multiple sclerosis (ReBUILD): a randomised, controlled, double-blind, crossover trial

Ari Green, Jeffrey M. Gelfand, Bruce Cree et al. · The Lancet · 2017 · 577 citations · Full text

, , +13

Quetiapine in Patients With Schizophrenia

Joyce G. Small · Archives of General Psychiatry · 1997 · 484 citations

, , +17

1–5 of 335

Authors

2.6K

  1. RG
    Ralf Gold

    St. Josef-Hospital, Germany

    37 publications · 5.1K citations

    26

    h-index

  2. RJ
    Robert J. Fox

    Cleveland Clinic, United States

    27 publications · 1.6K citations

    21

    h-index

  3. LK
    Ludwig Kappos

    University Hospital of Basel, Switzerland

    22 publications · 3.5K citations

    18

    h-index

  4. JT
    J. Theodore Phillips

    Biogen (United States), United States

    20 publications · 1.2K citations

    18

    h-index

  5. DL
    Douglas L. Arnold

    Montreal Neurological Institute and Hospital, Canada

    17 publications · 2.7K citations

    16

    h-index

1–5 of 2.6K

Institutions

809

  1. Biogen (United States)

    Cambridge, United States

    36 h-index

    322 publications

    37.9K citations

  2. St. Josef-Hospital

    Bochum, Germany

    24 h-index

    105 publications

    13.7K citations

  3. Cleveland Clinic

    Cleveland, United States

    22 h-index

    138 publications

    9.3K citations

  4. Ruhr University Bochum

    Bochum, Germany

    22 h-index

    71 publications

    13.8K citations

  5. McGill University

    Montreal, Canada

    17 h-index

    45 publications

    6.2K citations

  6. University Hospital of Basel

    Basel, Switzerland

    17 h-index

    27 publications

    3.3K citations

  7. Montreal Neurological Institute and Hospital

    Montreal, Canada

    17 h-index

    62 publications

    7.9K citations

  8. Queen Mary University of London

    London, United Kingdom

    16 h-index

    19 publications

    2.5K citations

1–8 of 809

Venues

  1. Neurology Neuroimmunology & Neuroinflammation

    17 publications · 891 citations

    16

    h-index

  2. Multiple Sclerosis Journal

    MSJ · 23 publications · 977 citations

    16

    h-index

  3. Multiple Sclerosis and Related Disorders

    16 publications · 487 citations

    13

    h-index

  4. Journal of Neurology

    12 publications · 539 citations

    12

    h-index

  5. Neurology and Therapy

    12 publications · 352 citations

    12

    h-index

1–5