Concepedia

Formulation-dependent Pharmacokinetics

Formulation-Dependent Pharmacokinetics is a pharmacokinetic phenomenon in pediatric drug disposition wherein the rate and extent of drug absorption and systemic exposure vary significantly due to differences in the pharmaceutical formulation of the same active ingredient, despite identical dosing regimens.

133

Publications

5.4K

Citations

702

Authors

244

Institutions

Publications per year

2017–2026

14

Parents

Publications

133

Reduced Inter- and Intraindividual Variability in Cyclosporine Pharmacokinetics from a Microemulsion Formulation

John M. Kovarik, Edgar A. Mueller, Klaus Kutz et al. · Journal of Pharmaceutical Sciences · 1994 · 300 citations

, , +15

Improved Dose Linearity of Cyclosporine Pharmacokinetics from a Microemulsion Formulation

Edgar A. Mueller, John M. Kovarik, Johannes B. van Bree et al. · Pharmaceutical Research · 1994 · 280 citations

, , +16

The Relation of Product Formulation to Absorption of Oral Theophylline

Miles Weinberger, Leslie Hendeles, Lyle D. Bighley et al. · New England Journal of Medicine · 1978 · 214 citations

, , +17

Enhanced Bioavailability of Itraconazole in Hydroxypropylβ-Cyclodextrin Solution versus Capsules in Healthy Volunteers

Joseph A. Barone, Bruce L. Moskovitz, Joseph A. Guarnieri et al. · Antimicrobial Agents and Chemotherapy · 1998 · 208 citations · Full text

, , +16

Influence of a Fat-Rich Meal on the Pharmacokinetics of a New Oral Formulation of Cyclosporine in a Crossover Comparison with the Market Formulation

Edgar A. Mueller, John M. Kovarik, Johannes B. van Bree et al. · Pharmaceutical Research · 1994 · 172 citations

, , +16

1–5 of 133

Authors

702

  1. KK
    Klaus Kutz

    Sanden (Japan), Japan

    4 publications · 796 citations

    4

    h-index

  2. EA
    Edgar A. Mueller

    Novartis (Switzerland), Switzerland

    3 publications · 752 citations

    3

    h-index

  3. IJ
    In‐Jin Jang

    Seoul National University Hospital, South Korea

    3 publications · 46 citations

    3

    h-index

  4. JB
    Johannes B. van Bree

    Jain PharmaBiotech (Switzerland), Switzerland

    3 publications · 752 citations

    3

    h-index

  5. FL
    Frank LaCreta

    Bristol-Myers Squibb (United States), United States

    3 publications · 63 citations

    3

    h-index

1–5 of 702

Institutions

244

  1. Seoul National University Hospital

    Seoul, South Korea

    3 h-index

    28 publications

    426 citations

  2. Janssen (Belgium)

    Beerse, Belgium

    3 h-index

    5 publications

    342 citations

  3. Bristol-Myers Squibb (Sweden)

    Solna, Sweden

    3 h-index

    3 publications

    63 citations

  4. Université de Montréal

    Montreal, Canada

    3 h-index

    12 publications

    296 citations

  5. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    3 h-index

    12 publications

    337 citations

  6. University at Buffalo, State University of New York

    Buffalo, United States

    3 h-index

    4 publications

    179 citations

  7. Merck & Co., Inc., Rahway, NJ, USA (United States)

    Rahway, United States

    3 h-index

    6 publications

    661 citations

  8. Bristol-Myers Squibb (United States)

    New York, United States

    3 h-index

    19 publications

    400 citations

1–8 of 244

Venues

  1. Clinical Therapeutics

    24 publications · 509 citations

    14

    h-index

  2. Journal of Pharmaceutical Sciences

    9 publications · 599 citations

    9

    h-index

  3. PubMed

    Repository · 9 publications · 357 citations

    9

    h-index

  4. International Journal of Pharmaceutics

    7 publications · 428 citations

    7

    h-index

  5. Clinical Drug Investigation

    6 publications · 100 citations

    6

    h-index

1–5