Concepedia

Force-dependent Bond Dynamics

Force-Dependent Bond Dynamics is a theoretical framework in cell adhesion mechanics that characterizes the mechanosensitive behavior of molecular bonds by modeling their formation, stabilization, and rupture as functions of applied mechanical forces, thereby distinguishing it from static or force-independent bond models.

79

Publications

10.1K

Citations

297

Authors

144

Institutions

Publications per year

2017–2026

17

Parents

Publications

79

Force-induced activation of covalent bonds in mechanoresponsive polymeric materials

Douglas A. Davis, Andrew Hamilton, Jinglei Yang et al. · Nature · 2009 · 1.7K citations

, , +16

Energy landscapes of receptor–ligand bonds explored with dynamic force spectroscopy

Rudolf Merkel, Pierre Nassoy, A. Leung et al. · Nature · 1999 · 1.7K citations

, , +16

How Strong Is a Covalent Bond?

Michel Grandbois, Martin K. Beyer, Matthias Rief et al. · Science · 1999 · 1.1K citations

, , +17

Lifetime of the P-selectin-carbohydrate bond and its response to tensile force in hydrodynamic flow

R. Alon, Daniel A. Hammer, Timothy A. Springer · Nature · 1995 · 717 citations

, , +12

Mechanical switching and coupling between two dissociation pathways in a P-selectin adhesion bond

Evan Evans, Andrew Leung, Volkmar Heinrich et al. · Proceedings of the National Academy of Sciences · 2004 · 324 citations · Full text

, , +17

1–5 of 79

Authors

297

  1. RM
    Rudolf Merkel

    Forschungszentrum Jülich, Germany

    4 publications · 1.8K citations

    4

    h-index

  2. CZ
    Cheng Zhu

    Georgia Institute of Technology, United States

    3 publications · 518 citations

    3

    h-index

  3. DA
    Daniel A. Hammer

    University of Pennsylvania, United States

    3 publications · 910 citations

    3

    h-index

  4. EE
    Evan Evans

    University of British Columbia, Canada

    3 publications · 674 citations

    3

    h-index

  5. HE
    Hermann E. Gaub

    Ludwig-Maximilians-Universität München, Germany

    3 publications · 1.1K citations

    3

    h-index

1–5 of 297

Institutions

144

  1. Boston University

    Boston, United States

    4 h-index

    10 publications

    4K citations

  2. Technical University of Munich

    Munich, Germany

    4 h-index

    11 publications

    2.6K citations

  3. University of Pennsylvania

    Philadelphia, United States

    4 h-index

    11 publications

    1.6K citations

  4. University of British Columbia

    Vancouver, Canada

    4 h-index

    14 publications

    10.9K citations

  5. Johannes Gutenberg University Mainz

    Mainz, Germany

    3 h-index

    6 publications

    188 citations

  6. Duke University

    Durham, United States

    3 h-index

    14 publications

    934 citations

  7. Georgia Institute of Technology

    Atlanta, United States

    3 h-index

    13 publications

    2K citations

  8. Ludwig-Maximilians-Universität München

    Munich, Germany

    3 h-index

    13 publications

    4.6K citations

1–8 of 144

Venues

  1. Biophysical Journal

    6 publications · 517 citations

    6

    h-index

  2. Nature Communications

    5 publications · 351 citations

    5

    h-index

  3. Journal of the American Chemical Society

    JACS · 5 publications · 458 citations

    5

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 5 publications · 1K citations

    5

    h-index

  5. Nature

    5 publications · 4.2K citations

    5

    h-index

1–5