Concepedia

Folding Pathway Determinants

Folding Pathway Determinants is a biochemical construct that identifies specific amino acid sequence features governing the temporal and mechanistic routes by which a polypeptide chain acquires its native three-dimensional structure during protein folding.

168

Publications

11.7K

Citations

562

Authors

175

Institutions

Publications per year

2017–2026

10

Parents

Publications

168

Atomic-Level Characterization of the Structural Dynamics of Proteins

David E. Shaw, Paul Maragakis, Kresten Lindorff‐Larsen et al. · Science · 2010 · 1.9K citations

, , +17

Synonymous codon substitutions affect ribosome traffic and protein folding during in vitro translation

Anton A. Komar, Thierry Lesnik, Claude Reiss · FEBS Letters · 1999 · 395 citations

, , +17

Engineered disulfide bonds as probes of the folding pathway of barnase: Increasing the stability of proteins against the rate of denaturation

Jane Clarke, Alan R. Fersht · Biochemistry · 1993 · 344 citations

, , +17

Crystal Structure of P22 Tailspike Protein: Interdigitated Subunits in a Thermostable Trimer

Stefan Steinbacher, Robert Seckler, Stefan Miller et al. · Science · 1994 · 317 citations

, , +16

Specific aggregation of partially folded polypeptide chains: The molecular basis of inclusion body composition

Margaret A. Speed, Daniel I. C. Wang, Jonathan King · Nature Biotechnology · 1996 · 311 citations

, , +17

1–5 of 168

Authors

562

  1. DP
    David P. Goldenberg

    University of Utah, United States

    7 publications · 366 citations

    7

    h-index

  2. JC
    Jane Clarke

    University of Cambridge, United Kingdom

    7 publications · 924 citations

    7

    h-index

  3. JK
    Jonathan King

    Massachusetts Institute of Technology, United States

    7 publications · 766 citations

    7

    h-index

  4. TE
    Thomas E. Creighton

    MRC Laboratory of Molecular Biology, United Kingdom

    6 publications · 592 citations

    6

    h-index

  5. JK
    Jonathan King

    Massachusetts Institute of Technology, United States

    5 publications · 239 citations

    5

    h-index

1–5 of 562

Institutions

175

  1. Massachusetts Institute of Technology

    Cambridge, United States

    11 h-index

    31 publications

    3K citations

  2. MRC Laboratory of Molecular Biology

    Cambridge, United Kingdom

    6 h-index

    12 publications

    1.1K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    24 publications

    2K citations

  4. University of Cambridge

    Cambridge, United Kingdom

    5 h-index

    20 publications

    1.7K citations

  5. University of Utah

    Salt Lake City, United States

    5 h-index

    9 publications

    601 citations

  6. Johns Hopkins University

    Baltimore, United States

    5 h-index

    6 publications

    245 citations

  7. Institut Pasteur

    Paris, France

    5 h-index

    15 publications

    572 citations

  8. Cornell University

    Ithaca, United States

    4 h-index

    16 publications

    419 citations

1–8 of 175

Venues

  1. Journal of Molecular Biology

    JMB · 27 publications · 1.8K citations

    24

    h-index

  2. Journal of Biological Chemistry

    JBC · 23 publications · 1K citations

    21

    h-index

  3. Biochemistry

    22 publications · 1.3K citations

    17

    h-index

  4. Protein Science

    PS · 14 publications · 450 citations

    12

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 11 publications · 902 citations

    11

    h-index

1–5