Concepedia

Fluorogenic Tetrazine Probes

Fluorogenic Tetrazine Probes is a chemical probe that belongs to the class of bioorthogonal reagents, distinguished by its ability to undergo a tetrazine ligation with strained alkenes or alkynes resulting in the selective turn-on of fluorescence due to the disruption of a quenching mechanism intrinsic to the tetrazine ring system.

66

Publications

6.1K

Citations

285

Authors

122

Institutions

Publications per year

2017–2026

41

Parents

Publications

66

Tetrazine-Based Cycloadditions: Application to Pretargeted Live Cell Imaging

Neal K. Devaraj, Ralph Weissleder, Scott A. Hilderbrand · Bioconjugate Chemistry · 2008 · 840 citations · Full text

, , +16

Biomedical Applications of Tetrazine Cycloadditions

Neal K. Devaraj, Ralph Weissleder · Accounts of Chemical Research · 2011 · 512 citations · Full text

, , +17

Fast and Sensitive Pretargeted Labeling of Cancer Cells through a Tetrazine/ <i>trans</i> ‐Cyclooctene Cycloaddition

Neal K. Devaraj, Rabi Upadhyay, Jered B. Haun et al. · Angewandte Chemie International Edition · 2009 · 372 citations · Full text

, , +17

BODIPY–Tetrazine Derivatives as Superbright Bioorthogonal Turn‐on Probes

Jonathan Carlson, Labros G. Meimetis, Scott A. Hilderbrand et al. · Angewandte Chemie International Edition · 2013 · 328 citations · Full text

, , +10

Ultrafluorogenic Coumarin–Tetrazine Probes for Real‐Time Biological Imaging

Labros G. Meimetis, Jonathan Carlson, Randy J. Giedt et al. · Angewandte Chemie International Edition · 2014 · 247 citations · Full text

, , +17

1–5 of 66

Authors

285

  1. HW
    Haoxing Wu

    Sichuan University, China

    10 publications · 1.1K citations

    10

    h-index

  2. XL
    Xiaogang Liu

    Singapore University of Technology and Design, Singapore

    9 publications · 401 citations

    9

    h-index

  3. NK
    Neal K. Devaraj

    University of California San Diego, United States

    9 publications · 2.7K citations

    9

    h-index

  4. RW
    Ralph Weissleder

    Massachusetts General Hospital, United States

    7 publications · 2.5K citations

    7

    h-index

  5. JY
    Jun Yang

    University of California San Diego, United States

    5 publications · 441 citations

    5

    h-index

1–5 of 285

Institutions

122

  1. Singapore University of Technology and Design

    Singapore, Singapore

    9 h-index

    25 publications

    1.1K citations

  2. Center for Systems Biology

    Boston, United States

    7 h-index

    28 publications

    8.7K citations

  3. Massachusetts General Hospital

    Boston, United States

    7 h-index

    28 publications

    8.7K citations

  4. University of California San Diego

    San Diego, United States

    7 h-index

    21 publications

    3K citations

  5. Sichuan University

    Chengdu, China

    6 h-index

    33 publications

    1.7K citations

  6. West China Hospital of Sichuan University

    Chengdu, China

    6 h-index

    31 publications

    1.6K citations

  7. HUN-REN Research Centre for Natural Sciences

    Budapest, Hungary

    5 h-index

    20 publications

    1K citations

  8. Harvard University

    Cambridge, United States

    4 h-index

    6 publications

    3.5K citations

1–8 of 122

Venues

  1. Angewandte Chemie International Edition

    13 publications · 1.8K citations

    13

    h-index

  2. Angewandte Chemie

    7 publications · 365 citations

    7

    h-index

  3. Chemical Communications

    ChemComm · 7 publications · 335 citations

    7

    h-index

  4. Chemical Science

    5 publications · 383 citations

    5

    h-index

  5. Journal of the American Chemical Society

    JACS · 4 publications · 546 citations

    4

    h-index

1–5