Concepedia

Flavin-containing Monooxygenation

Flavin-Containing Monooxygenation is a phase I metabolic reaction mechanism that belongs to the class of monooxygenase enzymes, distinguished by its reliance on flavin adenine dinucleotide (FAD) as a cofactor to catalyze the insertion of one atom of molecular oxygen into a substrate, typically resulting in oxygenation of nucleophilic heteroatoms such as nitrogen, sulfur, or phosphorus.

19

Publications

1.1K

Citations

91

Authors

29

Institutions

Publications per year

2017–2026

3

Parents

Publications

19

Missense mutation in flavin-containing mono-oxygenase 3 gene, FMO3, underlies fish-odour syndrome

Colin T. Dolphin, Azara Janmohamed, Robert L. Smith et al. · Nature Genetics · 1997 · 292 citations

, , +11

Mechanism of action of a flavin-containing monooxygenase

Subramaniam Eswaramoorthy, J.B. Bonanno, S.K. Burley et al. · Proceedings of the National Academy of Sciences · 2006 · 195 citations · Full text

, , +16

Identification of Novel Variants of the Flavin-Containing Monooxygenase Gene Family in African Americans

Bjarte Furnes, Jinong Feng, Steve S. Sommer et al. · Drug Metabolism and Disposition · 2003 · 68 citations

, , +15

Effect of Genetic Variants of the Human Flavin-Containing Monooxygenase 3 on N- and S-Oxygenation Activities

Makiko Shimizu, Hiroshi Yano, Satomi Nagashima et al. · Drug Metabolism and Disposition · 2006 · 57 citations

, , +13

Evaluation of Xenobiotic N- and S-Oxidation by Variant Flavin-Containing Monooxygenase 1 (FMO1) Enzymes

Bjarte Furnes · Toxicological Sciences · 2004 · 56 citations · Full text

, , +14

1–5 of 19

Authors

91

  1. DS
    Daniel Schlenk

    University of California, Riverside, United States

    4 publications · 124 citations

    4

    h-index

  2. BF
    Bjarte Furnes

    University of California, Riverside, United States

    3 publications · 135 citations

    3

    h-index

  3. MC
    Marilyn C. Henderson

    Oregon State University, United States

    2 publications · 29 citations

    2

    h-index

  4. SK
    Sharon K. Krueger

    Oregon State University, United States

    2 publications · 29 citations

    2

    h-index

  5. DE
    David E. Williams

    University of British Columbia, Canada

    2 publications · 29 citations

    2

    h-index

1–5 of 91

Institutions

29

  1. University of California, Riverside

    Riverside, United States

    4 h-index

    12 publications

    280 citations

  2. Oregon State University

    Corvallis, United States

    2 h-index

    14 publications

    189 citations

  3. University of California, San Francisco

    San Francisco, United States

    2 h-index

    2 publications

    73 citations

  4. Allergan (United States)

    Madison, United States

    1 h-index

    5 publications

    90 citations

  5. University of Pavia

    Pavia, Italy

    1 h-index

    3 publications

    96 citations

  6. University College London

    London, United Kingdom

    1 h-index

    2 publications

    584 citations

  7. University of Mississippi

    Oxford, United States

    1 h-index

    1 publications

    11 citations

  8. Brookhaven National Laboratory

    Upton, United States

    1 h-index

    2 publications

    390 citations

1–8 of 29

Venues

  1. Drug Metabolism and Disposition

    3 publications · 136 citations

    3

    h-index

  2. Chemical Research in Toxicology

    3 publications · 83 citations

    3

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 221 citations

    2

    h-index

  4. Chemical Science

    1 publications · 49 citations

    1

    h-index

  5. Plant Science

    1 publications · 31 citations

    1

    h-index

1–5