Concepedia

First-order Elimination Models

First-Order Elimination Models is a pharmacokinetic modeling framework in which the rate of drug elimination from the body is directly proportional to its current concentration, distinguishing it from zero-order models by exhibiting concentration-dependent clearance kinetics.

283

Publications

12K

Citations

1.5K

Authors

581

Institutions

Publications per year

2017–2026

77

Parents

Publications

283

Kinetic model for gentamicin dosing with the use of individual patient parameters

Ronald J. Sawchuk, Darwin E. Zaske, Robert J. Cipolle et al. · Clinical Pharmacology & Therapeutics · 1977 · 303 citations

, , +17

Acute dose-dependent effects of lysergic acid diethylamide in a double-blind placebo-controlled study in healthy subjects

Friederike Holze, Patrick Vizeli, Laura Ley et al. · Neuropsychopharmacology · 2020 · 243 citations · Full text

, , +12

Acetaminophen Developmental Pharmacokinetics in Premature Neonates and Infants

Brian J. Anderson, Richard A. van Lingen, Tom G. Hansen et al. · Anesthesiology · 2002 · 242 citations · Full text

, , +17

Intranasal and oral cocaine kinetics

Paul K. Wilkinson, Craig Van Dyke, Peter Jatlow et al. · Clinical Pharmacology & Therapeutics · 1980 · 230 citations

, , +17

General Treatment of Linear Mammillary Models with Elimination from any Compartment as Used in Pharmacokinetics

Leslie Z. Benet · Journal of Pharmaceutical Sciences · 1972 · 200 citations

, , +14

1–5 of 283

Authors

1.5K

  1. ÉJ
    Évelyne Jacqz-Aigrain

    Hôpital Robert-Debré, France

    11 publications · 358 citations

    11

    h-index

  2. WZ
    Wei Zhao

    Shandong University, China

    10 publications · 304 citations

    10

    h-index

  3. BJ
    Brian J. Anderson

    University of Auckland, New Zealand

    9 publications · 625 citations

    9

    h-index

  4. NH
    Nicholas H. G. Holford

    University of Auckland, New Zealand

    6 publications · 685 citations

    6

    h-index

  5. JM
    Jasmina Milovanović

    University of Kragujevac, Serbia

    5 publications · 101 citations

    5

    h-index

1–5 of 1.5K

Institutions

581

  1. Hôpital Robert-Debré

    Paris, France

    11 h-index

    30 publications

    1.1K citations

  2. University of Auckland

    Auckland, New Zealand

    11 h-index

    27 publications

    2.9K citations

  3. Université Paris Cité

    Paris, France

    11 h-index

    29 publications

    779 citations

  4. Assistance Publique – Hôpitaux de Paris

    Paris, France

    11 h-index

    40 publications

    1.3K citations

  5. Inserm

    Paris, France

    11 h-index

    31 publications

    1.4K citations

  6. University at Buffalo, State University of New York

    Buffalo, United States

    9 h-index

    16 publications

    494 citations

  7. University of Washington

    Seattle, United States

    7 h-index

    21 publications

    1.4K citations

  8. Shandong University

    Jinan, China

    7 h-index

    31 publications

    788 citations

1–8 of 581

Venues

  1. Antimicrobial Agents and Chemotherapy

    AAC · 46 publications · 1.9K citations

    28

    h-index

  2. British Journal of Clinical Pharmacology

    BJCP · 18 publications · 873 citations

    16

    h-index

  3. The Journal of Clinical Pharmacology

    19 publications · 925 citations

    15

    h-index

  4. Clinical Pharmacology & Therapeutics

    CPT · 15 publications · 970 citations

    13

    h-index

  5. Therapeutic Drug Monitoring

    15 publications · 446 citations

    13

    h-index

1–5