FIP200 Function is a molecular scaffolding mechanism within the autophagy initiation pathway that specifically mediates the assembly and activation of the ULK1 kinase complex through direct interaction with upstream regulators and downstream effectors.
89
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485
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44
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89
ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy
Ian G. Ganley, Du Lam, Junru Wang et al. · Journal of Biological Chemistry · 2009 · 1.5K citations · Full text
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177
University of Michigan
Ann Arbor, United States
16 h-index
61 publications
12.2K citations
University of Cincinnati Medical Center
Cincinnati, United States
11 h-index
45 publications
2.6K citations
Tokyo Medical and Dental University
Tokyo, Japan
8 h-index
27 publications
23.7K citations
University of California, Berkeley
Berkeley, United States
8 h-index
23 publications
1.7K citations
Max Perutz Labs
Vienna, Austria
7 h-index
43 publications
7.4K citations
Research Network (United States)
Kennesaw, United States
7 h-index
52 publications
2.2K citations
QB3
San Francisco, United States
7 h-index
22 publications
1.7K citations
University of Vienna
Vienna, Austria
7 h-index
42 publications
7.4K citations
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- Autophagy
12 publications · 2K citations
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- The Journal of Cell Biology
JCB · 10 publications · 2.1K citations
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- Nature Communications
5 publications · 613 citations
5
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- bioRxiv (Cold Spring Harbor Laboratory)
Repository · 4 publications · 65 citations
5
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- Molecular Biology of the Cell
MBC · 4 publications · 4.3K citations
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