Concepedia

Fibrin Structure-function Relationships

Fibrin Structure-Function Relationships is a theoretical framework that elucidates how the hierarchical molecular architecture of fibrin, including its polymerization dynamics, fiber elasticity, and cross-linking specificity, governs its biomechanical stability, clot porosity, and cellular interactions in hemostasis and thrombosis.

342

Publications

20.3K

Citations

1.2K

Authors

400

Institutions

Publications per year

2017–2026

32

Parents

Publications

342

Nanoparticle-induced unfolding of fibrinogen promotes Mac-1 receptor activation and inflammation

Zhou J. Deng, Mingtao Liang, Michael J. Monteiro et al. · Nature Nanotechnology · 2010 · 876 citations

, , +14

Soft fibrin gels promote selection and growth of tumorigenic cells

Jing Liu, Youhua Tan, Huafeng Zhang et al. · Nature Materials · 2012 · 475 citations · Full text

, , +14

Heparin-binding domain of fibrin(ogen) binds growth factors and promotes tissue repair when incorporated within a synthetic matrix

Mikaël M. Martino, Priscilla S. Briquez, Adrian Ranga et al. · Proceedings of the National Academy of Sciences · 2013 · 469 citations · Full text

, , +17

Lipoprotein(a), fibrin binding, and plasminogen activation.

Joseph Loscalzo, Michael S. Weinfeld, G M Fless et al. · Arteriosclerosis An Official Journal of the American Heart Association Inc · 1990 · 465 citations · Full text

, , +15

Angiogenic sprouting and capillary lumen formation modeled by human umbilical vein endothelial cells (HUVEC) in fibrin gels: the role of fibroblasts and Angiopoietin-1☆

Martin N. Nakatsu, Richard C.A. Sainson, Jason Aoto et al. · Microvascular Research · 2003 · 446 citations

, , +15

1–5 of 342

Authors

1.2K

  1. RF
    Russell F. Doolittle

    University of California San Diego, United States

    14 publications · 1.3K citations

    14

    h-index

  2. JW
    John W. Weisel

    University of Pennsylvania, United States

    14 publications · 1.3K citations

    14

    h-index

  3. RA
    Robert A.S. Ariëns

    University of Leeds, United Kingdom

    13 publications · 1.4K citations

    13

    h-index

  4. LM
    Leonid Medved

    American Red Cross, United States

    12 publications · 734 citations

    12

    h-index

  5. ST
    Susan T. Lord

    University of North Carolina at Chapel Hill, United States

    12 publications · 533 citations

    11

    h-index

1–5 of 1.2K

Institutions

400

  1. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    17 h-index

    68 publications

    3.6K citations

  2. University of Pennsylvania

    Philadelphia, United States

    14 h-index

    66 publications

    6.1K citations

  3. University of Leeds

    Leeds, United Kingdom

    13 h-index

    62 publications

    7.5K citations

  4. University of California San Diego

    San Diego, United States

    13 h-index

    34 publications

    2.2K citations

  5. Karolinska Institutet

    Stockholm, Sweden

    12 h-index

    32 publications

    2.8K citations

  6. American Red Cross

    Washington, United States

    9 h-index

    32 publications

    2.1K citations

  7. Temple University

    Philadelphia, United States

    8 h-index

    21 publications

    759 citations

  8. University of Washington

    Seattle, United States

    8 h-index

    22 publications

    964 citations

1–8 of 400

Venues

  1. Thrombosis Research

    35 publications · 1.4K citations

    23

    h-index

  2. Journal of Biological Chemistry

    JBC · 23 publications · 1.6K citations

    22

    h-index

  3. Blood

    36 publications · 2K citations

    21

    h-index

  4. Biochemistry

    27 publications · 1.7K citations

    20

    h-index

  5. Thrombosis and Haemostasis

    19 publications · 652 citations

    15

    h-index

1–5