Concepedia

Fed-batch Process Scale-up

Fed-Batch Process Scale-Up is a methodological framework within bioprocess engineering that systematically enlarges fed-batch cultivation systems from laboratory to industrial scale by dynamically regulating nutrient feed rates to maintain optimal metabolic conditions while addressing non-linear scalability challenges inherent in bioreactor systems.

50

Publications

2.2K

Citations

232

Authors

91

Institutions

Publications per year

2017–2026

15

Parents

Publications

50

Strategies for Improved dCO <sub>2</sub> Removal in Large‐Scale Fed‐Batch Cultures

Sigma S. Mostafa, Xuejun Gu · Biotechnology Progress · 2003 · 112 citations

, , +17

High‐level protein expression in scalable CHO transient transfection

Jianxin Ye, Vanessa Kober, Melanie Tellers et al. · Biotechnology and Bioengineering · 2009 · 107 citations

, , +17

Biodegradation of wool waste and keratinase production in scale-up fermenter with different strategies by Stenotrophomonas maltophilia BBE11-1

Zhen Fang, Juan Zhang, Baihong Liu et al. · Bioresource Technology · 2013 · 102 citations · Full text

, , +17

Fed‐batch bioreactor process scale‐up from 3‐L to 2,500‐L scale for monoclonal antibody production from cell culture

Jeng‐Dar Yang, Canghai Lu, Brad Stasny et al. · Biotechnology and Bioengineering · 2007 · 99 citations

, , +17

Integration of microbial kinetics and fluid dynamics toward model‐driven scale‐up of industrial bioprocesses

Guan Wang, Wenjun Tang, Jianye Xia et al. · Engineering in Life Sciences · 2014 · 90 citations

, , +17

1–5 of 50

Authors

232

  1. PN
    Peter Neubauer

    Technische Universität Berlin, Germany

    4 publications · 189 citations

    4

    h-index

  2. AW
    Alvin W. Nienow

    University of Birmingham, United Kingdom

    2 publications · 90 citations

    2

    h-index

  3. CJ
    Christopher J. Hewitt

    University of Birmingham, United Kingdom

    2 publications · 90 citations

    2

    h-index

  4. JŠ
    Juozas Šiurkus

    Technische Universität Berlin, Germany

    2 publications · 102 citations

    2

    h-index

  5. RD
    Roderich D. Süßmuth

    Technische Universität Berlin, Germany

    1 publications · 48 citations

    1

    h-index

1–5 of 232

Institutions

91

  1. Technische Universität Berlin

    Berlin, Germany

    4 h-index

    11 publications

    535 citations

  2. East China University of Science and Technology

    Shanghai, China

    3 h-index

    16 publications

    546 citations

  3. University of Birmingham

    Birmingham, United Kingdom

    2 h-index

    4 publications

    232 citations

  4. Technical University of Denmark

    Kongens Lyngby, Denmark

    2 h-index

    9 publications

    378 citations

  5. Eli Lilly (United States)

    Indianapolis, United States

    2 h-index

    5 publications

    350 citations

  6. Delft University of Technology

    Delft, The Netherlands

    2 h-index

    2 publications

    149 citations

  7. Jiangnan University

    Wuxi, China

    2 h-index

    6 publications

    526 citations

  8. University of Münster

    Münster, Germany

    1 h-index

    1 publications

    37 citations

1–8 of 91

Venues

  1. Biotechnology and Bioengineering

    7 publications · 502 citations

    7

    h-index

  2. Microbial Cell Factories

    7 publications · 352 citations

    7

    h-index

  3. Biotechnology Progress

    4 publications · 189 citations

    4

    h-index

  4. Biochemical Engineering Journal

    BEJ · 4 publications · 100 citations

    4

    h-index

  5. Journal of Biotechnology

    2 publications · 38 citations

    2

    h-index

1–5