Concepedia

Exposure-response Analysis

Exposure-Response Analysis is a pharmacometric method that characterizes the quantitative relationship between drug exposure, typically measured as plasma concentration or dose, and the magnitude of pharmacological effects, distinguishing it from other modeling approaches by its focus on linking kinetic profiles to dynamic outcomes for optimizing dosing regimens.

1.2K

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64.9K

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1.5K

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Publications per year

2017–2026

292

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1.2K

Distributed lag non‐linear models

Antonio Gasparrini, Ben Armstrong, Michael G. Kenward · Statistics in Medicine · 2010 · 2.5K citations · Full text

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Methods for Trend Estimation from Summarized Dose-Response Data, with Applications to Meta-Analysis

Sander Greenland, Matthew P. Longnecker · American Journal of Epidemiology · 1992 · 2.3K citations

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Use of an aggregate exposure model to estimate consumer exposure to fragrance ingredients in personal care and cosmetic products

B. Safford, A.M. Api, Christopher L. R. Barratt et al. · Regulatory Toxicology and Pharmacology · 2015 · 1.9K citations

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Meta-Analysis for Linear and Nonlinear Dose-Response Relations: Examples, an Evaluation of Approximations, and Software

Nicola Orsini, Ruifeng Li, Alicja Wolk et al. · American Journal of Epidemiology · 2011 · 1.3K citations · Full text

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Generalized Least Squares for Trend Estimation of Summarized Dose–response Data

Nicola Orsini, Rino Bellocco, Sander Greenland · The Stata Journal Promoting communications on statistics and Stata · 2006 · 1.2K citations · Full text

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Authors

5K

  1. HZ
    Honghui Zhou

    Janssen (United States), United States

    12 publications · 378 citations

    11

    h-index

  2. CN
    Charles N. Haas

    Drexel University, United States

    9 publications · 919 citations

    9

    h-index

  3. OJ
    Omoniyi J. Adedokun

    Janssen (United States), United States

    9 publications · 608 citations

    9

    h-index

  4. CH
    Chuanpu Hu

    Janssen (United States), United States

    9 publications · 236 citations

    9

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  5. WJ
    William J. Sandborn

    University of California San Diego, United States

    8 publications · 620 citations

    8

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1–5 of 5K

Institutions

1.5K

  1. Environmental Protection Agency

    Washington, United States

    29 h-index

    165 publications

    7.9K citations

  2. Research Triangle Park Foundation

    Durham, United States

    28 h-index

    139 publications

    7.2K citations

  3. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    20 h-index

    41 publications

    2.1K citations

  4. Pfizer (United States)

    New York, United States

    19 h-index

    92 publications

    7K citations

  5. Johns Hopkins University

    Baltimore, United States

    18 h-index

    58 publications

    2.9K citations

  6. Harvard University

    Cambridge, United States

    18 h-index

    44 publications

    4K citations

  7. Utrecht University

    Utrecht, The Netherlands

    18 h-index

    49 publications

    1.9K citations

  8. Roche (Switzerland)

    Basel, Switzerland

    15 h-index

    47 publications

    2K citations

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Venues

  1. Environmental Health Perspectives

    EHP · 43 publications · 2.1K citations

    26

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  2. PubMed

    Repository · 44 publications · 1.9K citations

    25

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  3. Toxicology and Applied Pharmacology

    TAAP · 30 publications · 1.7K citations

    23

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  4. Regulatory Toxicology and Pharmacology

    RTP · 36 publications · 3K citations

    22

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  5. Clinical Pharmacology & Therapeutics

    CPT · 26 publications · 1.7K citations

    20

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