Concepedia

Export Defects

Export Defects is a molecular phenomenon in which aberrant processing or transport of mature mRNA molecules from the nucleus to the cytoplasm disrupts normal gene expression, typically due to mutations or dysregulation in the nuclear pore complex or mRNA export machinery.

42

Publications

3.2K

Citations

166

Authors

70

Institutions

Publications per year

2017–2026

1

Parents

Publications

42

Suppressor mutations that restore export of a protein with a defective signal sequence

Scott D. Emr, Susan Hanley-Way, Thomas J. Silhavy · Cell · 1981 · 382 citations

, , +7

Stable mRNP Formation and Export Require Cotranscriptional Recruitment of the mRNA Export Factors Yra1p and Sub2p by Hpr1p

Daniel Zenklusen, Patrizia Vinciguerra, Jean-Christophe Wyss et al. · Molecular and Cellular Biology · 2002 · 310 citations · Full text

, , +16

Evidence for specificity at an early step in protein export in Escherichia coli

Carol A. Kumamoto, Jon Beckwith · Journal of Bacteriology · 1985 · 268 citations · Full text

, , +12

Salmonella typhimurium mutants defective in flagellar filament regrowth and sequence similarity of FliI to F0F1, vacuolar, and archaebacterial ATPase subunits

Alfried P. Vogler, Mitsuo Homma, V M Irikura et al. · Journal of Bacteriology · 1991 · 198 citations · Full text

, , +14

Perinuclear Mlp proteins downregulate gene expression in response to a defect in mRNA export

Patrizia Vinciguerra, Nahid Iglesias, Jurgi Camblong et al. · The EMBO Journal · 2005 · 144 citations · Full text

, , +16

1–5 of 42

Authors

166

  1. CA
    Carol A. Kumamoto

    Tufts University, United States

    4 publications · 403 citations

    4

    h-index

  2. DZ
    Daniel Zenklusen

    Université de Montréal, Canada

    3 publications · 586 citations

    3

    h-index

  3. AA
    Andrés Aguilera

    Universidad de Sevilla, Spain

    3 publications · 189 citations

    3

    h-index

  4. RL
    Rosa Luna

    Universidad de Sevilla, Spain

    3 publications · 189 citations

    3

    h-index

  5. FS
    Françoise Stutz

    University of Geneva, Switzerland

    3 publications · 586 citations

    3

    h-index

1–5 of 166

Institutions

70

  1. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    4 h-index

    11 publications

    636 citations

  2. Tufts University

    Medford, United States

    3 h-index

    7 publications

    508 citations

  3. California Institute of Technology

    Pasadena, United States

    3 h-index

    9 publications

    414 citations

  4. Harvard University

    Cambridge, United States

    3 h-index

    5 publications

    1.1K citations

  5. National Institute of Diabetes and Digestive and Kidney Diseases

    Bethesda, United States

    3 h-index

    4 publications

    262 citations

  6. National Institutes of Health

    Bethesda, United States

    3 h-index

    7 publications

    458 citations

  7. Universidad de Sevilla

    Seville, Spain

    3 h-index

    12 publications

    700 citations

  8. State University of New York

    Albany, United States

    2 h-index

    4 publications

    196 citations

1–8 of 70

Venues

  1. Journal of Biological Chemistry

    JBC · 12 publications · 711 citations

    12

    h-index

  2. Journal of Bacteriology

    JB · 8 publications · 728 citations

    8

    h-index

  3. Molecular and Cellular Biology

    MCB · 5 publications · 601 citations

    5

    h-index

  4. Molecular Biology of the Cell

    MBC · 2 publications · 104 citations

    2

    h-index

  5. Genetics

    2 publications · 128 citations

    2

    h-index

1–5