Evolutionary Rate Modeling is a computational framework within Profile Hidden Markov Models that characterizes the variation in substitution rates across sites in molecular sequences by integrating phylogenetic information and probabilistic emission and transition parameters to infer evolutionary constraints.
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An Improved General Amino Acid Replacement Matrix
Si Quang Le, Olivier Gascuel · Molecular Biology and Evolution · 2008 · 3.3K citations · Full text
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- SLSergei L. Kosakovsky Pond
University of California San Diego, United States
4 publications · 898 citations
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Harvard University
Cambridge, United States
5 h-index
6 publications
794 citations
KU Leuven
Leuven, Belgium
5 h-index
9 publications
502 citations
Centre National de la Recherche Scientifique
Paris, France
5 h-index
8 publications
6.7K citations
Rega Institute for Medical Research
Leuven, Belgium
5 h-index
10 publications
512 citations
Yale University
New Haven, United States
5 h-index
7 publications
180 citations
The University of Texas at Austin
Austin, United States
5 h-index
10 publications
459 citations
National Institutes of Health
Bethesda, United States
5 h-index
10 publications
1.9K citations
University of California, Los Angeles
Los Angeles, United States
5 h-index
11 publications
765 citations
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- Molecular Biology and Evolution
MBE · 16 publications · 6.4K citations
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- Journal of Molecular Evolution
8 publications · 33.4K citations
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- Systematic Biology
7 publications · 463 citations
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- Bioinformatics
7 publications · 1K citations
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- Genome Biology and Evolution
GBE · 4 publications · 137 citations
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