Concepedia

Enzyme Promiscuity Engineering

Enzyme Promiscuity Engineering is a methodological framework within enzyme design that involves the targeted modification of an enzyme's active site to expand or alter its substrate or catalytic promiscuity, thereby enabling the controlled execution of non-native biochemical reactions while retaining structural and functional integrity.

17

Publications

452

Citations

93

Authors

36

Institutions

Publications per year

2017–2026

12

Parents

Publications

17

Recent advances in enzyme promiscuity

Sustainable Chemical Processes · 2016 · 73 citations · Full text

, , +17

Exploiting the Potential of Meroterpenoid Cyclases to Expand the Chemical Space of Fungal Meroterpenoids

Takaaki Mitsuhashi, Lena Barra, Zachary Powers et al. · Angewandte Chemie International Edition · 2020 · 41 citations · Full text

, , +17

Establishing an Artificial Pathway for <i>De Novo</i> Biosynthesis of Vanillyl Alcohol in <i>Escherichia coli</i>

Zhenya Chen, Xiaolin Shen, Jian Wang et al. · ACS Synthetic Biology · 2017 · 41 citations

, , +15

Computationally Driven Rational Design of Substrate Promiscuity on Serine Ester Hydrolases

Sergi Rodà, Laura Fernández-López, Rubén Cañadas et al. · ACS Catalysis · 2021 · 37 citations · Full text

, , +17

Tuning the Properties of Natural Promiscuous Enzymes by Engineering Their Nano-environment

Carolina I. Giunta, Isabel Cea‐Rama, Sandra Alonso et al. · ACS Nano · 2020 · 36 citations

, , +17

1–5 of 17

Authors

93

  1. QY
    Qipeng Yuan

    Beijing University of Chemical Technology, China

    3 publications · 84 citations

    3

    h-index

  2. YY
    Yajun Yan

    University of Georgia, United States

    3 publications · 84 citations

    3

    h-index

  3. CW
    Chunyu Wang

    Jilin University, China

    2 publications · 28 citations

    2

    h-index

  4. TK
    Takashi Kikuchi

    Osaka University of Pharmaceutical Sciences, Japan

    2 publications · 55 citations

    2

    h-index

  5. FY
    Feng Yang

    Fudan University, China

    2 publications · 55 citations

    2

    h-index

1–5 of 93

Institutions

36

  1. University of California, Davis

    Davis, United States

    3 h-index

    5 publications

    141 citations

  2. University of Georgia

    Athens, United States

    3 h-index

    10 publications

    309 citations

  3. Beijing University of Chemical Technology

    Beijing, China

    3 h-index

    10 publications

    309 citations

  4. The University of Tokyo

    Tokyo, Japan

    2 h-index

    8 publications

    220 citations

  5. National Institutes of Natural Sciences

    Tokyo, Japan

    2 h-index

    4 publications

    110 citations

  6. University of Chinese Academy of Sciences

    Beijing, China

    2 h-index

    7 publications

    133 citations

  7. Institute for Molecular Science

    Okazaki, Japan

    2 h-index

    4 publications

    110 citations

  8. Boston University

    Boston, United States

    2 h-index

    8 publications

    220 citations

1–8 of 36

Venues

  1. ACS Synthetic Biology

    3 publications · 84 citations

    3

    h-index

  2. Methods in molecular biology

    Book series · 1 publications · 31 citations

    1

    h-index

  3. Sustainable Chemical Processes

    1 publications · 73 citations

    1

    h-index

  4. Angewandte Chemie International Edition

    1 publications · 41 citations

    1

    h-index

  5. ACS Nano

    1 publications · 36 citations

    1

    h-index

1–5